Safety and effectiveness of laparoscopic renal biopsy: a single-center review and meta-analysis.

IF 3 3区医学 Q1 UROLOGY & NEPHROLOGY Renal Failure Pub Date : 2024-12-01 Epub Date: 2024-02-02 DOI:10.1080/0886022X.2024.2312536

Lingling Xu, Xueqin Bian, Jian Yang, Hongying Xu, Yi Fang, Junwei Yang, Lei Jiang, Ping Wen

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Abstract

Background: While renal biopsy remains the preferred diagnostic method for assessing proteinuria, hematuria, or renal failure, laparoscopic renal biopsy (LRB) can serve as an alternative for high-risk patients when percutaneous kidney biopsy (PKB) is not recommended. This study was aimed to evaluate the safety of LRB.

Methods: In study 1, Fourteen patients from January 2021 to January 2023 had a LRB taken for various indications, such as morbid obesity, abnormal kidney construction, uncontrolled hypertension, and coagulopathy. We also conducted a Meta-analysis of the success rate and complication rate of previous LRB in study 2.

Results: All the patients completed biopsies and adequate renal tissues were obtained. The success rate was 100%. The median number of glomeruli obtained was 22.5 (range:12.0, 45.0). The complication rate was 7.1% (urinary tract infection). There were no significant differences between levels of hemoglobin, serum creatinine, and urinary NAGL before and after surgery. In the meta-analysis, the success rate of operation, satisfactory rate of sample, and complication rate of surgery were 99.9%, 99.1%, and 2.6% respectively.

Conclusion: LRB can achieve a good success rate and specimen retrieval and does not increase the risk of complications for high-risk patients. It can present as one of the alternative methods for patients with glomerular diseases.

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腹腔镜肾活检的安全性和有效性：单中心回顾和荟萃分析。

背景：虽然肾活检仍是评估蛋白尿、血尿或肾衰竭的首选诊断方法，但对于不推荐经皮肾活检（PKB）的高风险患者，腹腔镜肾活检（LRB）可作为一种替代方法。本研究旨在评估腹腔镜肾活检的安全性：在研究 1 中，2021 年 1 月至 2023 年 1 月期间，14 名患者因病态肥胖、肾脏结构异常、未控制的高血压和凝血功能障碍等不同适应症进行了 LRB 检查。在研究 2 中，我们还对既往 LRB 的成功率和并发症发生率进行了 Meta 分析：结果：所有患者都完成了活检，并获得了足够的肾组织。成功率为 100%。获得的肾小球数量中位数为 22.5 个（范围：12.0 至 45.0）。并发症发生率为 7.1%（尿路感染）。手术前后的血红蛋白、血清肌酐和尿NAGL水平无明显差异。在荟萃分析中，手术成功率、样本满意率和并发症发生率分别为 99.9%、99.1% 和 2.6%：结论：LRB 可实现良好的成功率和标本取回率，并且不会增加高危患者出现并发症的风险。结论：LRB 可实现良好的成功率和标本取回率，且不会增加高危患者出现并发症的风险，可作为肾小球疾病患者的替代方法之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Renal Failure 医学-泌尿学与肾脏学

CiteScore

3.90

自引率

13.30%

发文量

374

审稿时长

1 months

期刊介绍： Renal Failure primarily concentrates on acute renal injury and its consequence, but also addresses advances in the fields of chronic renal failure, hypertension, and renal transplantation. Bringing together both clinical and experimental aspects of renal failure, this publication presents timely, practical information on pathology and pathophysiology of acute renal failure; nephrotoxicity of drugs and other substances; prevention, treatment, and therapy of renal failure; renal failure in association with transplantation, hypertension, and diabetes mellitus.