Substance Use Disorders among Adolescents in the United States: 2000-2019.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL Southern Medical Journal Pub Date : 2024-02-01 DOI:10.14423/SMJ.0000000000001655

Brook T Alemu, Hind A Baydoun, Olaniyi Olayinka, Robyn M Treadwell

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引用次数: 0

Abstract

Objectives: Substance use disorders (SUDs) are characterized by impairment caused by the recurrent use of alcohol, illicit drugs, or both. SUDs are pervasive and endemic among US adolescents, with potentially negative health and social consequences. Although the term experimentation normalizes adolescent substance abuse, the long-term consequences of this behavior beginning in adolescence can be detrimental to not only the adolescent but also the adult into which he or she develops. Our objective was to examine the epidemiology of SUD among hospitalized US adolescents, 13 to 19 years of age, during the time period 2000-2019.

Methods: A case-control study was conducted using 5,260,104 hospital discharge records (394,952 SUD and 4,865,152 non-SUD) from the 2000-2019 Kids' Inpatient Database. SUD and clinical outcomes variables were identified based on the International Classification of Diseases, Ninth/Tenth Revisions, Clinical Modification, coding. SUD rates (per 1000 discharges) were calculated and adjusted odds ratios (aORs) with their 95% confidence intervals (CIs) were computed using logistic regression models for predictors of SUDs among hospitalized adolescents.

Results: The prevalence of SUDs was estimated to be 75.10 cases per 1000 discharges (95% CI 74.86-75.31). Demographically, the highest crude rates (per 1000 discharges) were seen among Native American (139.58) and White (91.97) patients. Adolescent patients who experienced SUD were twice as likely as nonusers to be 16 to 19 years of age (aOR 2.2, 95% CI 2.13-2.19) or to be male (aOR 2.2, 95% CI 2.22-2.27). SUD was significantly associated with cooccurring conditions, including anxiety (aOR 2.5, 95% CI 2.48-2.53), depression (aOR 2.3, 95% CI 2.30-2.35), mood disorder (aOR 2.17, 95% CI 2.14-2.20), schizophrenia (aOR 2.6, 95% CI 2.52-2.64), sexually transmitted infections (aOR 2.3, 95% CI 2.23-2.45), hepatitis (aOR 3.0, 95% CI 2.87-3.15), and suicide (aOR 1.33, 95% CI 1.30-1.35).

Conclusions: The study examined the epidemiology, risk factors, and common characteristics of hospitalized adolescent patients with SUDs. The high burden of psychiatric and medical comorbidities observed among this patient group warrants designing effective and comprehensive substance use prevention and treatment programs for youths.

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美国青少年的药物使用障碍：2000-2019.

目标：物质使用障碍（SUDs）的特征是反复使用酒精、非法药物或同时使用这两种药物所造成的损伤。药物滥用障碍在美国青少年中普遍存在，具有潜在的健康和社会负面影响。虽然 "尝试 "一词将青少年药物滥用正常化，但这种行为从青少年时期就开始了，其长期后果不仅会对青少年造成伤害，也会对其成长为成年人造成伤害。我们的目的是研究 2000-2019 年期间住院的美国 13 至 19 岁青少年中 SUD 的流行病学：我们利用 2000-2019 年儿童住院患者数据库中的 5,260,104 份出院记录（394,952 份 SUD 记录和 4,865,152 份非 SUD 记录）开展了一项病例对照研究。SUD 和临床结果变量根据《国际疾病分类》第九版/第十版修订版、临床修订版编码确定。使用逻辑回归模型计算了住院青少年的 SUD 发生率（每 1000 例出院者），并计算了调整后的几率比（aOR）及其 95% 的置信区间（CI）：据估计，每 1000 名出院者中 SUDs 患病率为 75.10 例（95% CI 74.86-75.31）。从人口统计学角度来看，美国原住民（139.58 例）和白人（91.97 例）患者的粗发病率（每 1000 例出院者）最高。经历过 SUD 的青少年患者中，16 至 19 岁（aOR 2.2，95% CI 2.13-2.19）或男性（aOR 2.2，95% CI 2.22-2.27）的可能性是未使用者的两倍。SUD 与焦虑症（aOR 2.5，95% CI 2.48-2.53）、抑郁症（aOR 2.3，95% CI 2.30-2.35）、情绪障碍（aOR 2.17，95% CI 2.14-2.20）、精神分裂症（aOR 2.2，95% CI 2.22-2.27）等并发症密切相关。20）、精神分裂症（aOR 2.6，95% CI 2.52-2.64）、性传播感染（aOR 2.3，95% CI 2.23-2.45）、肝炎（aOR 3.0，95% CI 2.87-3.15）和自杀（aOR 1.33，95% CI 1.30-1.35）：本研究探讨了住院青少年 SUD 患者的流行病学、风险因素和共同特征。研究发现，这一患者群体的精神和医疗合并症负担较重，因此有必要为青少年设计有效、全面的药物使用预防和治疗计划。

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来源期刊

Southern Medical Journal 医学-医学：内科

CiteScore

1.40

自引率

9.10%

发文量

222

审稿时长

4-8 weeks

期刊介绍： As the official journal of the Birmingham, Alabama-based Southern Medical Association (SMA), the Southern Medical Journal (SMJ) has for more than 100 years provided the latest clinical information in areas that affect patients'' daily lives. Now delivered to individuals exclusively online, the SMJ has a multidisciplinary focus that covers a broad range of topics relevant to physicians and other healthcare specialists in all relevant aspects of the profession, including medicine and medical specialties, surgery and surgery specialties; child and maternal health; mental health; emergency and disaster medicine; public health and environmental medicine; bioethics and medical education; and quality health care, patient safety, and best practices. Each month, articles span the spectrum of medical topics, providing timely, up-to-the-minute information for both primary care physicians and specialists. Contributors include leaders in the healthcare field from across the country and around the world. The SMJ enables physicians to provide the best possible care to patients in this age of rapidly changing modern medicine.