Dietary Salt Can Be Crucial for Food-Induced Vascular Inflammation.

IF 1.9 Q3 PATHOLOGY Clinical Pathology Pub Date : 2024-02-03 eCollection Date: 2024-01-01 DOI:10.1177/2632010X241228039
Syed Masudur Rahman Dewan, Sara Shahid Meem, Amrin Yeasin Proma, Mohammad Shahriar
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Abstract

Salt enhances the taste as well as the nutritional value of food. Besides, several reports are available on the incidence and epidemiology of various illnesses in relation to salt intake. Excessive salt consumption has been found to be linked with high blood pressure, renal disease, and other cardiovascular disorders due to the result of vascular inflammation. Nevertheless, studies aimed at elucidating the molecular processes that produce vascular inflammation have yet to reach their conclusions. This article emphasizes the significance of investigating the mechanisms underlying both acute and chronic vascular inflammation induced by salt. It also explores the logical inferences behind cellular oxidative stress and the role of endothelial dysfunction as the potential initiator of the inflammatory segments that remain poorly understood. It is therefore hypothesized that salt is one of the causes of chronic vascular inflammation such as atherosclerosis. The hypothesis's secrets, when revealed, can help assure cardiovascular health by proactive efforts and the development of appropriate preventative measures, in combination with medication, dietary and lifestyle adjustments.

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膳食盐对食物诱发的血管炎症至关重要
食盐能提升食物的口感和营养价值。此外,有多份报告指出,各种疾病的发病率和流行病学与食盐摄入量有关。研究发现,过量摄入食盐与高血压、肾病和其他心血管疾病有关,这些疾病是血管炎症的结果。然而,旨在阐明产生血管炎症的分子过程的研究尚未得出结论。本文强调了研究盐诱发急性和慢性血管炎症机制的重要性。文章还探讨了细胞氧化应激背后的逻辑推理,以及内皮功能障碍作为炎症环节潜在启动器的作用,但这些问题仍然鲜为人知。因此,假设盐是动脉粥样硬化等慢性血管炎症的原因之一。一旦揭示了这一假设的秘密,就可以通过积极的努力和制定适当的预防措施,结合药物、饮食和生活方式的调整,帮助确保心血管健康。
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来源期刊
Clinical Pathology
Clinical Pathology PATHOLOGY-
CiteScore
2.20
自引率
7.70%
发文量
66
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