Chronic and Neurotropic: A Paradigm-Challenging Case of Dengue Virus Encephalitis in a Patient With Advanced HIV Infection.

IF 8.2 1区 医学 Q1 IMMUNOLOGY Clinical Infectious Diseases Pub Date : 2024-08-16 DOI:10.1093/cid/ciae061
Tina Marinelli, Jeffrey Masters, Michael E Buckland, Maggie Lee, William Rawlinson, Ki Wook Kim, Nicolas Urriola, Sebastiaan van Hal
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Abstract

A 32-year-old female with advanced human immunodeficiency virus infection presented to an Australian hospital with subacute, worsening symptoms of encephalitis. Metagenomic sequencing and Dengue NS3 antigen staining of brain tissue confirmed active dengue virus (DENV) encephalitis. The most recent possible DENV exposure was months prior in West Africa, indicating chronicity.

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慢性和神经性:人类免疫缺陷病毒感染晚期患者登革病毒脑炎的范例挑战。
一名 32 岁的女性艾滋病毒感染晚期患者因亚急性脑炎症状加重而到澳大利亚一家医院就诊。脑组织的元基因组测序和登革热 NS3 抗原染色证实了活动性登革热病毒(DENV)脑炎。最近一次可能的登革热病毒接触是几个月前在西非,这表明该病是慢性的。
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来源期刊
Clinical Infectious Diseases
Clinical Infectious Diseases 医学-传染病学
CiteScore
25.00
自引率
2.50%
发文量
900
审稿时长
3 months
期刊介绍: Clinical Infectious Diseases (CID) is dedicated to publishing original research, reviews, guidelines, and perspectives with the potential to reshape clinical practice, providing clinicians with valuable insights for patient care. CID comprehensively addresses the clinical presentation, diagnosis, treatment, and prevention of a wide spectrum of infectious diseases. The journal places a high priority on the assessment of current and innovative treatments, microbiology, immunology, and policies, ensuring relevance to patient care in its commitment to advancing the field of infectious diseases.
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