Managing Monkeypox Virus Infections: A Contemporary Review.

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Iranian Journal of Medical Sciences Pub Date : 2024-01-01 DOI:10.30476/IJMS.2022.96738.2837
Fariba Asadi Noghabi, John G Rizk, Dheeraj Makkar, Nasibeh Roozbeh, Soleyman Ghelichpour, Aref Zarei
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Abstract

Monkeypox is an infectious and contagious zoonotic disease caused by the Orthopoxvirus species and was first identified in Africa. Recently, this infectious disease has spread widely in many parts of the world. Fever, fatigue, headache, and rash are common symptoms of monkeypox. The presence of lymphadenopathy is another prominent and key symptom of monkeypox, which distinguishes this disease from other diseases and is useful for diagnosing the disease. This disease is transmitted to humans through contact with or eating infected animals as well as objects infected with the virus. One of the ways to diagnose this disease is through PCR testing of lesions and secretions. To prevent the disease, vaccines such as JYNNEOS and ACAM2000 are available, but they are not accessible to all people in the world, and their effectiveness and safety need further investigation. However, preventive measures such as avoiding contact with people infected with the virus and using appropriate personal protective equipment are mandatory. The disease therapy is based on medicines such as brincidofovir, cidofovir, and Vaccinia Immune Globulin Intravenous. The injectable format of tecovirimat was approved recently, in May 2022. Considering the importance of clinical care in this disease, awareness about the side effects of medicines, nutrition, care for conjunctivitis, skin rash, washing and bathing at home, and so on can be useful in controlling and managing the disease.

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猴痘病毒感染管理:当代回顾。
猴痘是一种由正痘病毒引起的人畜共患传染病,最早发现于非洲。最近,这种传染病在世界许多地方广泛传播。发热、疲劳、头痛和皮疹是猴痘的常见症状。淋巴结肿大是猴痘另一个突出的主要症状,可将这种疾病与其他疾病区分开来,有助于诊断这种疾病。这种疾病会通过接触或食用受感染的动物以及受病毒感染的物体传染给人类。诊断这种疾病的方法之一是对病变和分泌物进行 PCR 检测。为了预防这种疾病,目前已有 JYNNEOS 和 ACAM2000 等疫苗,但并非全世界所有人都能接种,其有效性和安全性还需要进一步研究。不过,避免与病毒感染者接触和使用适当的个人防护设备等预防措施是必须的。该病的治疗以药物为基础,如布林昔多福韦、西多福韦和疫苗免疫球蛋白静脉注射。最近,泰考韦酯的注射剂型于 2022 年 5 月获得批准。考虑到临床护理在该疾病中的重要性,了解药物的副作用、营养、结膜炎的护理、皮疹、家庭洗浴等知识有助于控制和管理该疾病。
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来源期刊
Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
0.00%
发文量
84
审稿时长
12 weeks
期刊介绍: The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of com­muni­cation for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science re­search experiences on prevalent diseases in the region and analysis of various regional problems.
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