RESIDUAL GASTRIC VOLUME IN MORBIDLY OBESE DIABETICS AFTER AN OVERNIGHT FASTING OR 3 HOURS OF A CARBOHYDRATE-ENRICHED SUPPLEMENT: A RANDOMIZED CROSSOVER PILOT STUDY.

Gunther Peres Pimenta, Ozgur Dandin, Cervantes Caporossi, José Eduardo Aguilar Nascimento
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Abstract

Background: To reduce the risk of regurgitation during anesthesia for elective procedures, residual gastric volumes (RGV) have traditionally been minimized by overnight fasting. Prolonged preoperative fasting presents some adverse consequences and has been abandoned for most surgical procedures, except for obese and/or diabetic patients.

Aims: The aim of this study was to assess the RGV in morbidly obese diabetic patients after traditional or abbreviated fasting.

Methods: This study was approved by the Ethics Committee for Research with Human Beings from the Federal University of Mato Grosso, under number 179.017/2012. This is a prospective, randomized, and crossover design study in eight morbidly obese type II diabetic patients. RGV was measured endoscopically after either traditional overnight fasting of at least 8 hours, or after abbreviated fasting of 6 hours for solids and 3 hours for a drink containing water plus 25 g (12.5%) of maltodextrin. Data were expressed as mean and range and differences were compared with paired t-tests at p<0.05.

Results: The study population had a mean age of 41.5 years (28-53), weight of 135 kg (113-196), body mass index of 48.2 kg/m2 (40-62.4), and type II diabetes for 4.5 years (1-10). The RGV after abbreviated fasting was 21.5 ml (5-40) vs 26.3 ml (7-65) after traditional fasting. This difference was not significant (p=0.82).

Conclusions: Gastric emptying in morbidly obese diabetic patients is similar after either traditional or abbreviated fasting with a carbohydrate drink.

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病态肥胖的糖尿病患者在禁食一夜或服用富含碳水化合物的补充剂 3 小时后的残胃量:随机交叉试验研究。
背景:为降低择期手术麻醉期间反流的风险,传统上通过禁食一夜将残胃容积(RGV)降至最低。目的:本研究旨在评估病态肥胖的糖尿病患者在传统或简短禁食后的残胃容积:这项研究获得了马托格罗索联邦大学人体研究伦理委员会的批准,批准号为 179.017/2012。这是一项前瞻性、随机和交叉设计的研究,对象是八名病态肥胖的 II 型糖尿病患者。RGV是在传统隔夜禁食至少8小时后,或在简短禁食6小时固体食物和3小时含水加25克(12.5%)麦芽糊精的饮料后,通过内窥镜测量的。数据以平均值和范围表示,差异以配对 t 检验(pResults)进行比较:研究对象的平均年龄为 41.5 岁(28-53 岁),体重为 135 公斤(113-196 公斤),体重指数为 48.2 公斤/平方米(40-62.4 公斤),患 II 型糖尿病 4.5 年(1-10 年)。简短禁食后的 RGV 为 21.5 毫升(5-40),而传统禁食后为 26.3 毫升(7-65)。这一差异并不明显(P=0.82):病态肥胖的糖尿病患者在传统禁食或简短禁食并饮用碳水化合物饮料后的胃排空情况相似。
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