Clinical potential of fasting in type 1 diabetes.

IF 11.4 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Trends in Endocrinology and Metabolism Pub Date : 2024-05-01 Epub Date: 2024-02-07 DOI:10.1016/j.tem.2024.01.007
Krista A Varady, Mary-Claire Runchey, Sirimon Reutrakul, Alaina P Vidmar, Lisa S Chow
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Abstract

Most adults with type 1 diabetes (T1DM) are either overweight or obese. As such, dietary management is recommended as an adjunct to insulin treatment to improve glycemic control and facilitate weight loss in these patients. Time-restricted eating (TRE) is a form of intermittent fasting that offers a simplified approach to treating obesity in T1DM. TRE typically involves restricting eating to 6 to 10 h per day, with water and medications allowed outside the eating window. This review examines the efficacy of TRE and other fasting protocols in improving weight and glycemic control in patients with obesity and T1DM. This review will also evaluate the safety of these regimens and provide advice to clinicians on implementing intermittent fasting in T1DM.

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1 型糖尿病患者禁食的临床潜力。
大多数 1 型糖尿病(T1DM)成人患者都超重或肥胖。因此,建议将饮食管理作为胰岛素治疗的辅助手段,以改善血糖控制并促进这些患者的体重减轻。限时进食(TRE)是间歇性禁食的一种形式,为治疗 T1DM 患者的肥胖症提供了一种简化方法。限时进食通常是将进食时间限制在每天 6 到 10 小时,在进食时间之外允许喝水和服用药物。本综述探讨了 TRE 和其他禁食方案在改善肥胖和 T1DM 患者体重和血糖控制方面的疗效。本综述还将评估这些方案的安全性,并为临床医生在 T1DM 患者中实施间歇性禁食提供建议。
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来源期刊
Trends in Endocrinology and Metabolism
Trends in Endocrinology and Metabolism 医学-内分泌学与代谢
CiteScore
20.10
自引率
0.00%
发文量
98
审稿时长
82 days
期刊介绍: Trends in Endocrinology and Metabolism (TEM) stands as a premier Reviews journal in the realms of metabolism and endocrinology. Our commitment is reflected in the publication of refined, concise, and highly impactful articles that delve into cutting-edge topics, encompassing basic, translational, and clinical aspects. From state-of-the-art treatments for endocrine diseases to groundbreaking developments in molecular biology, TEM provides comprehensive coverage. Explore recent advancements in diabetes, endocrine diseases, obesity, neuroendocrinology, immunometabolism, molecular and cellular biology, and a myriad of other areas through our journal. TEM serves as an invaluable resource for researchers, clinicians, lecturers, teachers, and students. Each monthly issue is anchored by Reviews and Opinion articles, with Reviews meticulously chronicling recent and significant developments, often contributed by leading researchers in specific fields. Opinion articles foster debate and hypotheses. Our shorter pieces include Science & Society, shedding light on issues at the intersection of science, society, and policy; Spotlights, which focus on exciting recent developments in the literature, and single-point hypotheses as Forum articles. We wholeheartedly welcome and encourage responses to previously published TEM content in the form of Letters.
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