Identifying Ontarians with Type 2 Diabetes Mellitus in Administrative Data: A Comparison of Two Case Definitions.

IF 3.8 3区医学 Q2 Medicine Diabetes Therapy Pub Date : 2024-03-01 Epub Date: 2024-02-10 DOI:10.1007/s13300-024-01535-4

Robyn L Houlden, Nilasha Thayalan, Scott Shi, Atif Kukaswadia, Godfrey Mau, Aiden Liu

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Abstract

Introduction: This study compared two previously validated sensitive and specific diabetes case definitions to explore the impact of different classification methods in Ontario ICES administrative data.

Methods: This study included patients captured by the Ontario Diabetes Database with type 2 diabetes using either the sensitive cohort definition (≥ 2 physician visits for diabetes within 1 year or ≥ 1 drug claim for diabetes or ≥ 1 hospitalization with diabetes), or the specific cohort definition (≥ 3 physician visits for diabetes within 1 year), between October 1, 2013 to September 30, 2015. Each cohort's demographic and clinical features were described using descriptive analysis.

Results: Using sensitive and specific definitions, 1,093,812 and 783,228 patients with type 2 diabetes were identified, respectively. Overall, the demographic and clinical characteristics were similar between cohorts. Patients in the sensitive cohort had mean age of 64.1 years and were 52.4% male, compared to 64.8 years and 53.6% male in the specific cohort. In the sensitive and specific cohorts respectively, 64.4% and 55.7% of patients reported one-year mean HbA1c of < 7% (53 mmol/mol) and 25.3% and 31.5% reported levels between 7.0-8.5% (53-69 mmol/mol).

Conclusions: Although sample sizes were different between sensitive and specific cohorts, demographic and clinical characteristics were similar.

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从管理数据中识别安大略省 2 型糖尿病患者：两种病例定义的比较。

导言：本研究比较了之前验证的两种敏感和特异糖尿病病例定义，以探讨安大略省 ICES 行政数据中不同分类方法的影响：本研究纳入了安大略省糖尿病数据库在2013年10月1日至2015年9月30日期间使用敏感队列定义（1年内≥2次糖尿病就诊或≥1次糖尿病药物索赔或≥1次糖尿病住院）或特定队列定义（1年内≥3次糖尿病就诊）采集的2型糖尿病患者。通过描述性分析描述了每个队列的人口统计学和临床特征：采用敏感定义和特异定义，分别确定了 1,093,812 名和 783,228 名 2 型糖尿病患者。总体而言，两组患者的人口统计学特征和临床特征相似。敏感组群患者的平均年龄为 64.1 岁，男性占 52.4%，而特异组群患者的平均年龄为 64.8 岁，男性占 53.6%。在敏感组群和特异组群中，分别有 64.4% 和 55.7% 的患者报告一年的平均 HbA1c 为结论：虽然敏感组群和特异组群的样本量不同，但人口统计学和临床特征相似。

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来源期刊

Diabetes Therapy Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

6.90

自引率

7.90%

发文量

130

审稿时长

6 weeks

期刊介绍： Diabetes Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all areas of diabetes. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Diabetes Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.