Year in Review in Axial Spondyloarthritis Clinical Research and Guidelines: SPARTAN 2023 Annual Meeting Proceedings.

IF 5.7 2区 医学 Q1 RHEUMATOLOGY Current Rheumatology Reports Pub Date : 2024-05-01 Epub Date: 2024-02-10 DOI:10.1007/s11926-024-01134-z
Maureen Dubreuil
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Abstract

Purpose of review: To highlight high impact clinical publications in spondyloarthritis from May 2022 to April 2023 that were summarized and presented at the SPARTAN annual meeting in May 2023.

Recent findings: Publications included updated guidelines on management of axial spondyloarthritis (axSpA) by ASAS-EULAR and development of a modified Juvenile Spondyloarthritis Disease Activity Index (JSpADA). Definitions were published for MRI lesions of the spine in axSpA and active and structural sacroiliac (SI) joint lesions in juvenile spondyloarthritis (JSpA). Anatomic variants of the sacroiliac joint were commonly detected using synthetic CT derived from pelvis MRI images. Anti-CD74 antibodies hold promise as a diagnostic biomarker for axSpA; however, the mechanism of such antibody development seems unrelated to gastrointestinal inflammation. High impact clinical publications in spondyloarthritis addressed lab-based and imaging biomarkers, outcome measures, and updated management guidelines.

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轴性脊柱关节炎临床研究和指南年度回顾:SPARTAN 2023 年会论文集。
综述目的:重点介绍2022年5月至2023年4月期间发表的、在2023年5月SPARTAN年会上总结和展示的、具有重大影响的脊柱关节炎临床论文:出版物包括ASAS-EULAR更新的轴性脊柱关节炎(axSpA)管理指南,以及修订的青少年脊柱关节炎疾病活动指数(JSpADA)。公布了轴性脊柱炎(axSpA)脊柱磁共振成像病变和幼年脊柱关节炎(JSpA)骶髂关节(SI)活动性和结构性病变的定义。骶髂关节的解剖变异通常是通过骨盆 MRI 图像合成 CT 检测出来的。抗CD74抗体有望成为axSpA的诊断生物标志物;然而,这种抗体的产生机制似乎与胃肠道炎症无关。脊柱关节炎方面具有重大影响的临床出版物涉及基于实验室和成像的生物标记物、结果测量和更新的管理指南。
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期刊介绍: This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.
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