A Prospective Observational Study of Physical Activity Levels and Physical Fitness of People at High Risk for Lung Cancer

Asha Bonney MBBS , Catherine L. Granger PhD , Daniel Steinfort PhD , Henry M. Marshall PhD , Emily Stone PhD , Annette McWilliams PhD , Fraser Brims PhD , Paul Fogarty MBBS , Linda Lin MBBS , Jiashi Li MD , Siyuan Pang MD , Stephen Lam PhD , Kwun M. Fong PhD , Renee Manser PhD
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Abstract

Introduction

Physical activity (PA) is a potentially modifiable risk factor for lung cancer, with previous research revealing that people who engage in more PA have lower risk of developing lung cancer. PA levels of lung cancer screening participants have not previously been explored.

Methods

Participants at a single Australian International Lung Screen Trial site were eligible for assessment of self-reported PA levels (International Physical Activity Questionnaire and Physical Activity Scale for the Elderly) and physical assessments (6-min walk distance, hand grip muscle strength, daily step count, and body composition) at a single time point during lung cancer screening. Statistics were predominantly descriptive, with parametric data presented as mean and SD and nonparametric data presented as median and interquartile range (IQR).

Results

A total of 178 participants were enrolled in this study, with a median age of 61 years. Of the participants, 61% were men and 51% were people who currently smoke. The median total International Physical Activity Questionnaire score was 1756 MET/min/wk (IQR 689, 4049). Mean total Physical Activity Scale for the Elderly score was 160 (SD 72), higher than described in healthy sedentary adults. The median daily step count was 7237 steps (IQR 5353, 10,038) and mean 6-minute walk distance was 545 m (SD 92). Median grip strengths were within predicted normal range, with an elevated median percentage body fat and low skeletal muscle mass found on body composition.

Conclusion

Almost a quarter of International Lung Screen Trial participants assessed reported low levels of PA and have a potentially modifiable risk factor to improve health outcomes. Larger studies are needed to characterize the burden of inactivity among high-risk lung cancer screening populations.

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肺癌高危人群体育活动水平和体能的前瞻性观察研究
导言:体育锻炼(PA)是肺癌的潜在可调节风险因素,以往的研究表明,体育锻炼越多的人患肺癌的风险越低。方法澳大利亚一个国际肺筛查试验点的参与者有资格在肺癌筛查期间的一个时间点接受自我报告的体力活动水平评估(国际体力活动问卷和老年人体力活动量表)和体能评估(6 分钟步行距离、手握肌力、每日步数和身体成分)。统计数据以描述性为主,参数数据以平均值和标清值表示,非参数数据以中位数和四分位数间距(IQR)表示。其中 61% 为男性,51% 为吸烟者。国际体力活动问卷总分的中位数为 1756 MET/min/周(IQR 为 689,4049)。老年人体力活动量表的平均总分为 160 分(标准差 72 分),高于健康的久坐不动的成年人。每日步数中位数为 7237 步(IQR 为 5353 步至 10038 步),平均 6 分钟步行距离为 545 米(SD 为 92 米)。握力中位数在预测的正常范围内,身体成分中发现体脂百分比中位数升高,骨骼肌质量较低。需要进行更大规模的研究,以确定高风险肺癌筛查人群中缺乏运动的负担。
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来源期刊
CiteScore
4.20
自引率
0.00%
发文量
145
审稿时长
19 weeks
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