Risk factors for late postoperative bleeding after partial glossectomy for tongue cancer.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 Epub Date: 2024-02-12 DOI:10.1080/00016489.2024.2310695

Hidehito Matsui, Takashi Mukaigawa, Seiya Goto, Shinichi Okada, Yohei Hiiragi, Kota Wada

{"title":"Risk factors for late postoperative bleeding after partial glossectomy for tongue cancer.","authors":"Hidehito Matsui, Takashi Mukaigawa, Seiya Goto, Shinichi Okada, Yohei Hiiragi, Kota Wada","doi":"10.1080/00016489.2024.2310695","DOIUrl":null,"url":null,"abstract":"Background: Partial glossectomy is the most common procedure for early-stage tongue cancer. Although late postoperative bleeding occasionally occurs, the associated risk factors have not been adequately identified.Aims/objectives: We aimed to investigate the rate and risk factors for late postoperative bleeding after transoral partial glossectomy with or without neck dissection for tongue cancer at our institution.Material and methods: We analysed 211 patients who had undergone transoral partial glossectomy between January 2016 and January 2023. The potential risk factors associated with late postoperative bleeding were investigated using univariate and multivariate logistic regression analyses.Results: Of the 211 patients, 40 (19%) showed late postoperative bleeding, with 19 (9%) classified as grade IIIa (Clavien-Dindo classification). Regarding all grades, late postoperative bleeding was significantly higher in patients aged <70 years and in those with polyglycolic acid (PGA) sheets (p = .046 and .030, respectively). For grade ≥ IIIa, late postoperative bleeding was significantly higher in patients with a history of anticoagulant/platelet administration, a mucosal defect covered with fibrin glue and a PGA sheet (p = .045 and .026, respectively).Conclusions and significance: The findings of this study suggest that primary closure decreases the frequency of late postoperative bleeding.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00016489.2024.2310695","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/12 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Partial glossectomy is the most common procedure for early-stage tongue cancer. Although late postoperative bleeding occasionally occurs, the associated risk factors have not been adequately identified.

Aims/objectives: We aimed to investigate the rate and risk factors for late postoperative bleeding after transoral partial glossectomy with or without neck dissection for tongue cancer at our institution.

Material and methods: We analysed 211 patients who had undergone transoral partial glossectomy between January 2016 and January 2023. The potential risk factors associated with late postoperative bleeding were investigated using univariate and multivariate logistic regression analyses.

Results: Of the 211 patients, 40 (19%) showed late postoperative bleeding, with 19 (9%) classified as grade IIIa (Clavien-Dindo classification). Regarding all grades, late postoperative bleeding was significantly higher in patients aged <70 years and in those with polyglycolic acid (PGA) sheets (p = .046 and .030, respectively). For grade ≥ IIIa, late postoperative bleeding was significantly higher in patients with a history of anticoagulant/platelet administration, a mucosal defect covered with fibrin glue and a PGA sheet (p = .045 and .026, respectively).

Conclusions and significance: The findings of this study suggest that primary closure decreases the frequency of late postoperative bleeding.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

舌癌部分切除术后晚期出血的风险因素。

背景：舌部分切除术是治疗早期舌癌最常见的手术。虽然术后晚期出血偶有发生，但相关风险因素尚未充分确定：我们旨在调查本院舌癌经口部分舌体切除术（带或不带颈部切除术）术后晚期出血的发生率和风险因素：我们分析了2016年1月至2023年1月期间接受经口部分切除术的211名患者。采用单变量和多变量逻辑回归分析研究了与术后晚期出血相关的潜在风险因素：在211名患者中，有40人（19%）出现术后晚期出血，其中19人（9%）为IIIa级（Clavien-Dindo分类）。在所有等级中，术后晚期出血患者的年龄分别为 0.046 岁和 0.030 岁，明显高于其他患者。）对于≥IIIa级的患者，有抗凝剂/血小板用药史、粘膜缺损被纤维蛋白胶和PGA片覆盖的患者术后晚期出血量明显更高（p = .045和.026）：本研究结果表明，初次闭合可降低术后晚期出血的频率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.