Fungi in cancer

IF 72.5 1区 医学 Q1 ONCOLOGY Nature Reviews Cancer Pub Date : 2024-02-12 DOI:10.1038/s41568-024-00665-y
Jessica Galloway-Peña, Iliyan D. Iliev, Florencia McAllister
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Abstract

Both the gut and the tumour microbiome are now established as crucial regulators of cancer phenotypes and have been implicated in cancer initiation, progression and therapy response. Although the role of bacteria in these processes is beginning to be unravelled, the relevance of fungi is only just emerging. In this Viewpoint, we asked experts to discuss the current knowledge on the mycobiome–cancer connection and share their opinion on how to best solve open questions. In this Viewpoint article, we asked three scientists working on the cancer mycobiome to provide their opinions on advancements and challenges and what the future holds for this exciting field of cancer research.
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癌症中的真菌
肠道和肿瘤微生物组目前已被确定为癌症表型的关键调节因子,并与癌症的发生、发展和治疗反应有关。虽然细菌在这些过程中的作用已开始被揭示,但真菌的相关性才刚刚出现。在本视点文章中,我们请专家们讨论了有关真菌生物体与癌症之间联系的现有知识,并就如何最好地解决未决问题分享了他们的看法。在这篇 "视点 "文章中,我们请三位从事癌症真菌生物群研究的科学家就这一令人兴奋的癌症研究领域所取得的进展和面临的挑战以及未来的前景发表看法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Nature Reviews Cancer
Nature Reviews Cancer 医学-肿瘤学
CiteScore
111.90
自引率
0.40%
发文量
97
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.
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