Recent advances in the knowledge of the mechanism of reflux hypersensitivity.

IF 1.6 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Scandinavian Journal of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-02-11 DOI:10.1080/00365521.2024.2310177
Li Na Ying, Yan Sun, Li Yang Cui, Zhen Yu Zhang, Rui Fang Li, Jun Zhang
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引用次数: 0

Abstract

Reflux hypersensitivity (RH) is a subtype of gastroesophageal reflux disease. The Rome IV criteria separated RH from the original nonerosive reflux disease subgroup and classified it as a new functional oesophageal disease. Recently, the pathogenesis of RH has become the focus of research. According to the latest research reports, upregulation of acid-sensitive receptors, distribution of calcitonin gene-related peptide-positive nerve fibres, and psychiatric comorbidity have key roles in the pathogenesis of RH. This work reviews the latest findings regarding RH mechanisms.

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反流过敏机制知识的最新进展。
反流过敏症(RH)是胃食管反流病的一种亚型。罗马IV标准将RH从原来的非侵蚀性反流病亚组中分离出来,并将其归类为一种新的功能性食管疾病。最近,RH 的发病机制成为研究的焦点。根据最新的研究报告,酸敏感受体的上调、降钙素基因相关肽阳性神经纤维的分布以及精神疾病合并症在 RH 的发病机制中起着关键作用。本研究综述了有关 RH 发病机制的最新发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.40
自引率
5.30%
发文量
222
审稿时长
3-8 weeks
期刊介绍: The Scandinavian Journal of Gastroenterology is one of the most important journals for international medical research in gastroenterology and hepatology with international contributors, Editorial Board, and distribution
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