Trends in Twin Births and Survival in Bangladesh: An Analysis of Half a Century of Evidence.

IF 1 4区 医学 Q4 GENETICS & HEREDITY Twin Research and Human Genetics Pub Date : 2024-02-12 DOI:10.1017/thg.2024.5
Kazi Zubair Hossain, Iftekhar Hasan
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Abstract

This study assessed the trends in twin births and their survival in Bangladesh by analyzing over a quarter million live births during 1970-2018, pooled from all eight rounds of the Bangladesh Demographic and Health Survey. In these five decades, the twinning rate increased by 1.5 times, from 5.8 to 8.6 twins per 1000 maternities. The decadal twinning rates varied across maternal age, parity, body mass index, household wealth index, and geographic region. The gap in decadal neonatal, infant, and under-five cumulative survival probability between singleton and multiple births was found to be closing, using Kaplan-Meier curves. Child mortality decreased by 80% and 60% in singleton and multiple births respectively. However, the absolute size of child mortality in multiple births remained six times higher than in singletons and was concentrated in the neonatal period. The share of multiple births surged in all types of child mortality. We predict a further and faster rise in multiple births in the coming decades in the face of upward trends in maternal age overlapping with higher parities, education, career prospects, contraceptive use, and the future demand-supply of assisted reproductive technology. A particular focus on the improvement of perinatal and neonatal care with wider availability is warranted. Otherwise, increased multiple births might raise child mortality and create public health challenges.

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孟加拉国双胞胎出生和存活趋势:对半个世纪证据的分析。
本研究通过分析 1970-2018 年间超过 25 万名活产婴儿,汇集了所有八轮孟加拉国人口与健康调查的数据,评估了孟加拉国双胞胎出生及其存活率的趋势。在这五十年间,双胎率增长了 1.5 倍,从每 1000 名产妇中有 5.8 对双胞胎增加到 8.6 对。不同产妇的年龄、奇偶数、体重指数、家庭财富指数和地理区域的十年双胞胎率各不相同。利用 Kaplan-Meier 曲线发现,单胎与多胎之间的十年新生儿、婴儿和五岁以下儿童累积存活概率的差距正在缩小。单胎和多胎的儿童死亡率分别下降了 80% 和 60%。然而,多胞胎儿童死亡率的绝对值仍比单胎高出六倍,而且主要集中在新生儿期。在所有类型的儿童死亡率中,多胞胎所占的比例都急剧上升。我们预测,在未来几十年中,由于产妇年龄与高次均等、教育、职业前景、避孕药具的使用以及辅助生殖技术的未来供需等因素重叠,多胎妊娠将进一步加速增长。应特别重视改善围产期和新生儿护理,使其更加普及。否则,多胎妊娠的增加可能会提高儿童死亡率,给公共卫生带来挑战。
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来源期刊
Twin Research and Human Genetics
Twin Research and Human Genetics 医学-妇产科学
CiteScore
1.50
自引率
11.10%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.
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