Validation and Improvement of the Saga Fall Risk Model: A Multicenter Retrospective Observational Study.

IF 3.5 3区 医学 Q2 GERIATRICS & GERONTOLOGY Clinical Interventions in Aging Pub Date : 2024-02-07 eCollection Date: 2024-01-01 DOI:10.2147/CIA.S441235
Masaki Tago, Risa Hirata, Naoko E Katsuki, Eiji Nakatani, Midori Tokushima, Tomoyo Nishi, Hitomi Shimada, Shizuka Yaita, Chihiro Saito, Kaori Amari, Kazuya Kurogi, Yoshimasa Oda, Kiyoshi Shikino, Maiko Ono, Mariko Yoshimura, Shun Yamashita, Yoshinori Tokushima, Hidetoshi Aihara, Motoshi Fujiwara, Shu-Ichi Yamashita
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Abstract

Purpose: We conducted a pilot study in an acute care hospital and developed the Saga Fall Risk Model 2 (SFRM2), a fall prediction model comprising eight items: Bedriddenness rank, age, sex, emergency admission, admission to the neurosurgery department, history of falls, independence of eating, and use of hypnotics. The external validation results from the two hospitals showed that the area under the curve (AUC) of SFRM2 may be lower in other facilities. This study aimed to validate the accuracy of SFRM2 using data from eight hospitals, including chronic care hospitals, and adjust the coefficients to improve the accuracy of SFRM2 and validate it.

Patients and methods: This study included all patients aged ≥20 years admitted to eight hospitals, including chronic care, acute care, and tertiary hospitals, from April 1, 2018, to March 31, 2021. In-hospital falls were used as the outcome, and the AUC and shrinkage coefficient of SFRM2 were calculated. Additionally, SFRM2.1, which was modified from the coefficients of SFRM2 using logistic regression with the eight items comprising SFRM2, was developed using two-thirds of the data randomly selected from the entire population, and its accuracy was validated using the remaining one-third portion of the data.

Results: Of the 124,521 inpatients analyzed, 2,986 (2.4%) experienced falls during hospitalization. The median age of all inpatients was 71 years, and 53.2% were men. The AUC of SFRM2 was 0.687 (95% confidence interval [CI]:0.678-0.697), and the shrinkage coefficient was 0.996. SFRM2.1 was created using 81,790 patients, and its accuracy was validated using the remaining 42,731 patients. The AUC of SFRM2.1 was 0.745 (95% CI: 0.731-0.758).

Conclusion: SFRM2 showed good accuracy in predicting falls even on validating in diverse populations with significantly different backgrounds. Furthermore, the accuracy can be improved by adjusting the coefficients while keeping the model's parameters fixed.

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验证和改进 Saga 跌倒风险模型:一项多中心回顾性观察研究。
目的:我们在一家急症护理医院进行了一项试点研究,并开发出了由八个项目组成的跌倒预测模型--Saga跌倒风险模型2(SFRM2):该模型由八个项目组成:卧床等级、年龄、性别、急诊入院、神经外科入院、跌倒史、独立进食和使用催眠药。两家医院的外部验证结果表明,SFRM2 的曲线下面积(AUC)在其他医院可能较低。本研究旨在利用包括慢性病医院在内的八家医院的数据验证 SFRM2 的准确性,并调整系数以提高 SFRM2 的准确性并验证其准确性:本研究纳入了2018年4月1日至2021年3月31日期间八家医院(包括慢性病医院、急诊医院和三甲医院)收治的所有年龄≥20岁的患者。以院内跌倒为结局,计算 SFRM2 的 AUC 和收缩系数。此外,还使用从全部人群中随机抽取的三分之二数据开发了 SFRM2.1,该数据是根据 SFRM2 的系数使用逻辑回归对 SFRM2 的八个项目进行修正后得出的,并使用剩余的三分之一数据对其准确性进行了验证:在分析的 124,521 名住院患者中,有 2,986 人(2.4%)在住院期间发生过跌倒。所有住院患者的中位年龄为 71 岁,53.2% 为男性。SFRM2 的 AUC 为 0.687(95% 置信区间 [CI]:0.678-0.697),收缩系数为 0.996。SFRM2.1 是通过 81,790 名患者创建的,其准确性通过剩余的 42,731 名患者进行了验证。SFRM2.1的AUC为0.745(95% CI:0.731-0.758):结论:SFRM2 在预测跌倒方面表现出良好的准确性,即使在背景明显不同的不同人群中进行验证也是如此。此外,在保持模型参数不变的情况下,还可以通过调整系数来提高准确性。
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来源期刊
Clinical Interventions in Aging
Clinical Interventions in Aging GERIATRICS & GERONTOLOGY-
CiteScore
6.80
自引率
2.80%
发文量
193
审稿时长
6-12 weeks
期刊介绍: Clinical Interventions in Aging, is an online, peer reviewed, open access journal focusing on concise rapid reporting of original research and reviews in aging. Special attention will be given to papers reporting on actual or potential clinical applications leading to improved prevention or treatment of disease or a greater understanding of pathological processes that result from maladaptive changes in the body associated with aging. This journal is directed at a wide array of scientists, engineers, pharmacists, pharmacologists and clinical specialists wishing to maintain an up to date knowledge of this exciting and emerging field.
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