Acuity of asthma exacerbations in Alberta, Canada is increasing: a population-based study.

IF 2.6 4区 医学 Q2 ALLERGY Allergy Asthma and Clinical Immunology Pub Date : 2024-02-12 DOI:10.1186/s13223-024-00872-0
Adil Adatia, Jalal Moolji, Imran Satia
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Abstract

Background: Asthma is a common respiratory illness affecting 2.8 million Canadians, including 9.7% of Albertans. Prior studies showed a substantial decrease in ED visits for asthma in the decade preceding 2010, followed by a stabilization. This was attributed to improvements in the pharmacologic and non-pharmacologic treatments for asthma during that period followed by a balance between epidemiologic drivers and protective factors in the population.

Methods: We assessed whether this trend continued in Alberta from 2010 to 2022 using population level data for the volume of daily ED visits, acuity of asthma exacerbations in the ED, and hospitalization rate.

Results: The mean number of ED visits decreased from 4.5 to 2.2 per million persons per day, but the acuity of exacerbations and the proportion requiring hospitalization increased. The number of patients presenting with the highest level of acuity increased by over 300%, and the percentage of patients requiring hospitalization increased from 6.8 to 11.3%.

Conclusion: Total ED visits for asthma exacerbations continues to decline in Alberta. The reasons for an increase in more severe exacerbations requires further attention.

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加拿大艾伯塔省哮喘恶化的严重程度正在增加:一项基于人口的研究。
背景:哮喘是一种常见的呼吸道疾病,影响着 280 万加拿大人,其中包括 9.7% 的艾伯塔人。先前的研究表明,在 2010 年之前的十年中,因哮喘而到急诊室就诊的人数大幅减少,随后趋于稳定。这归因于在此期间哮喘的药物和非药物治疗有所改善,以及流行病学驱动因素和人口保护因素之间的平衡:我们利用艾伯塔省每日急诊室就诊量、急诊室哮喘加重的严重程度以及住院率等人口层面的数据,评估了 2010 年至 2022 年艾伯塔省的这一趋势是否持续:急诊室平均就诊人数从每天每百万人中 4.5 人次降至 2.2 人次,但哮喘加重的严重程度和需要住院治疗的比例却有所增加。病情最严重的患者人数增加了 300% 以上,需要住院治疗的患者比例从 6.8% 增加到 11.3%:结论:艾伯塔省因哮喘加重而前往急诊室就诊的总人数在继续下降。结论:艾伯塔省因哮喘加重而前往急诊室就诊的总人数在继续下降,但需要进一步关注更严重加重的原因。
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来源期刊
CiteScore
4.30
自引率
3.70%
发文量
96
审稿时长
12 weeks
期刊介绍: Allergy, Asthma & Clinical Immunology (AACI), the official journal of the Canadian Society of Allergy and Clinical Immunology (CSACI), is an open access journal that encompasses all aspects of diagnosis, epidemiology, prevention and treatment of allergic and immunologic disease. By offering a high-visibility forum for new insights and discussions, AACI provides a platform for the dissemination of allergy and clinical immunology research and reviews amongst allergists, pulmonologists, immunologists and other physicians, healthcare workers, medical students and the public worldwide. AACI reports on basic research and clinically applied studies in the following areas and other related topics: asthma and occupational lung disease, rhinoconjunctivitis and rhinosinusitis, drug hypersensitivity, allergic skin diseases, urticaria and angioedema, venom hypersensitivity, anaphylaxis and food allergy, immunotherapy, immune modulators and biologics, immune deficiency and autoimmunity, T cell and B cell functions, regulatory T cells, natural killer cells, mast cell and eosinophil functions, complement abnormalities.
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