Bringing At-home Pediatric Sleep Apnea Testing Closer to Reality: A Multi-modal Transformer Approach.

Hamed Fayyaz, Abigail Strang, Rahmatollah Beheshti
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Abstract

Sleep apnea in children is a major health problem affecting one to five percent of children (in the US). If not treated in a timely manner, it can also lead to other physical and mental health issues. Pediatric sleep apnea has different clinical causes and characteristics than adults. Despite a large group of studies dedicated to studying adult apnea, pediatric sleep apnea has been studied in a much less limited fashion. Relatedly, at-home sleep apnea testing tools and algorithmic methods for automatic detection of sleep apnea are widely present for adults, but not children. In this study, we target this gap by presenting a machine learning-based model for detecting apnea events from commonly collected sleep signals. We show that our method outperforms state-of-the-art methods across two public datasets, as determined by the F1-score and AUROC measures. Additionally, we show that using two of the signals that are easier to collect at home (ECG and SpO2) can also achieve very competitive results, potentially addressing the concerns about collecting various sleep signals from children outside the clinic. Therefore, our study can greatly inform ongoing progress toward increasing the accessibility of pediatric sleep apnea testing and improving the timeliness of the treatment interventions.

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让居家小儿睡眠呼吸暂停检测更接近现实:多模式变压器方法。
儿童睡眠呼吸暂停是一个重大的健康问题,影响着 1% 到 5% 的儿童(在美国)。如果不及时治疗,还可能导致其他身心健康问题。小儿睡眠呼吸暂停的临床原因和特点与成人不同。尽管有大量研究致力于研究成人呼吸暂停,但对小儿睡眠呼吸暂停的研究却少得多。与此相关的是,用于自动检测睡眠呼吸暂停的家用睡眠呼吸暂停测试工具和算法方法广泛应用于成人,但儿童却没有。在本研究中,我们针对这一空白,提出了一种基于机器学习的模型,用于从通常收集的睡眠信号中检测呼吸暂停事件。根据 F1 分数和 AUROC 指标,我们的方法在两个公共数据集上的表现优于最先进的方法。此外,我们还表明,使用两种在家中更容易收集的信号(ECG 和 SpO2)也能获得非常有竞争力的结果,从而有可能解决在诊所外收集儿童各种睡眠信号的问题。因此,我们的研究可以为不断提高小儿睡眠呼吸暂停检测的可及性和改善治疗干预的及时性提供重要信息。
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