Stellate ganglion block in the treatment of SAPHO syndrome: A case report.

IF 0.9 Q4 RHEUMATOLOGY Modern rheumatology case reports Pub Date : 2024-07-08 DOI:10.1093/mrcr/rxae008
Chenhao Jiang, Liangyu Cai, Jiannan Zhang, Hongmei Zhou
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Abstract

Synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare and refractory autoinflammatory disease, and there is no consensus on its treatment. Stellate ganglion block (SGB) blocks sympathetic nerves, ameliorates immune dysfunction, and alleviates stress response, which has been used to treat various chronic pain syndromes, arrhythmias, and post-traumatic stress disorder (PTSD). Also, the SGB has been reported to be successfully used to treat certain skin diseases, autoinflammatory diseases, and menopausal symptoms. In this study, over 3 years of follow-up, we found that SGB successfully intervened the symptoms of SAPHO syndrome, including sternoclavicular joint arthritis and palmoplantar pustulosis.

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星状神经节阻滞治疗 SAPHO 综合征:病例报告。
滑膜炎、痤疮、掌跖脓疱病、骨质增生和骨炎(SAPHO)综合征是一种罕见的难治性自身炎症性疾病,其治疗方法尚未达成共识。星状神经节阻滞(SGB)可阻滞交感神经,改善免疫功能紊乱,缓解应激反应,已被用于治疗各种慢性疼痛综合征、心律失常和创伤后应激障碍(PTSD)。此外,据报道,SGB 还可成功用于治疗某些皮肤病、自身炎症性疾病和更年期症状。在这项研究中,经过 3 年的随访,我们发现 SGB 成功干预了 SAPHO 综合征的症状,包括胸锁关节炎和掌跖脓疱病。
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