GRADE pearls and pitfalls-Part 1: Systematic reviews and meta-analyses.

IF 1.9 4区 医学 Q2 ANESTHESIOLOGY Acta Anaesthesiologica Scandinavica Pub Date : 2024-05-01 Epub Date: 2024-02-13 DOI:10.1111/aas.14386
Zainab Al Duhailib, Anders Granholm, Waleed Alhazzani, Simon Oczkowski, Emilie Belley-Cote, Morten Hylander Møller
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Abstract

Background: The Grading of Recommendation, Assessment, Development and Evaluation (GRADE) approach is used to assess the certainty of evidence in systematic reviews and meta-analyses.

Methods: We describe how the GRADE approach is used in systematic reviews and meta-analyses, including key points and examples. This overview is aimed at clinicians and researchers who are, or plan to be, involved in the development or assessment of systematic reviews with meta-analyses using GRADE.

Results: We outline how the certainty of evidence is assessed, how the evidence is summarized using GRADE evidence profiles or summary of findings tables, how the results are communicated, and we discuss challenges, advantages, and disadvantages with using GRADE.

Conclusions: This overview aims to provide an overview of how GRADE is used in systematic reviews and meta-analyses, and may be used by systematic review developers, methodologists, and evidence end-users.

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GRADE 珍珠和陷阱--第 1 部分:系统综述和荟萃分析。
背景:推荐、评估、发展和评价分级(GRADE)方法用于评估系统综述和荟萃分析中证据的确定性:推荐、评估、发展和评价分级法(GRADE)用于评估系统综述和荟萃分析中证据的确定性:我们介绍了 GRADE 方法在系统综述和荟萃分析中的应用,包括要点和实例。本综述面向正在或计划使用 GRADE 参与系统性综述和荟萃分析的开发或评估的临床医生和研究人员:我们概述了如何评估证据的确定性、如何使用 GRADE 证据概况或研究结果摘要表总结证据、如何交流结果,并讨论了使用 GRADE 所面临的挑战、优势和劣势:本综述旨在概述 GRADE 如何用于系统综述和荟萃分析,可供系统综述开发人员、方法论专家和证据最终用户使用。
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来源期刊
CiteScore
4.30
自引率
9.50%
发文量
157
审稿时长
3-8 weeks
期刊介绍: Acta Anaesthesiologica Scandinavica publishes papers on original work in the fields of anaesthesiology, intensive care, pain, emergency medicine, and subjects related to their basic sciences, on condition that they are contributed exclusively to this Journal. Case reports and short communications may be considered for publication if of particular interest; also letters to the Editor, especially if related to already published material. The editorial board is free to discuss the publication of reviews on current topics, the choice of which, however, is the prerogative of the board. Every effort will be made by the Editors and selected experts to expedite a critical review of manuscripts in order to ensure rapid publication of papers of a high scientific standard.
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