Primary Lacrimal Sac Tumors with Extension into Vicinity: Outcomes with Endoscopy-Assisted Modified Weber-Ferguson's Approach.

IF 1.7 4区 医学 Q3 OPHTHALMOLOGY Current Eye Research Pub Date : 2024-05-01 Epub Date: 2024-02-14 DOI:10.1080/02713683.2024.2306849
Leilei Zhang, Wenyue Zhang, Lunhao Li, XueRu Liu, Yi Ding, Fan Yang, Mohammad Javed Ali, Caiwen Xiao
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Abstract

Purpose: To evaluate the outcomes of endoscopy-assisted modified Weber-Ferguson's approach in the management of primary lacrimal sac tumors with extension into the neighboring tissues.

Methods: A retrospective interventional study was performed on all patients with lacrimal sac tumors treated with the endoscopy-assisted modified Weber-Ferguson approach between January 2010 and June 2022 at the Shanghai Ninth People's Hospital, China. Data assessed include demographics, clinical presentations, imaging features, surgical techniques, histopathology, adjuvant modalities of management, complications, and outcomes.

Results: A total of 13 patients were included in the analysis. Epiphora and palpable mass lesion were the presenting complaint in 84.6% (11/13) of the patients. Nearly half of the patients (46.1%, 6/13) were misdiagnosed as lacrimal duct obstruction. All the lacrimal sac tumors in the present series showed uneven enhancement on T1-weighted MRI imaging. Postoperatively, 84.6% (11/13) patients recovered well with excellent esthetics and were disease-free after a mean follow-up of 58.6 months. Two patients who underwent additional exenteration developed recurrence and succumbed (at 41 and 96 months follow up) while they were on palliative chemoradiation.

Conclusion: The endoscopic-assisted modified Weber-Fergusson surgical approach is effective in providing better visibility and accessibility to lacrimal sac tumors with extension into neighboring tissue.

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原发性泪囊肿瘤向邻近部位扩展:内镜辅助下的改良韦伯-弗格森法的疗效
目的:评估内镜辅助下改良韦伯-弗格森法治疗向邻近组织扩展的原发性泪囊肿瘤的效果:方法:对2010年1月至2022年6月期间在中国上海市第九人民医院接受内镜辅助改良韦伯-弗格森方法治疗的所有泪囊肿瘤患者进行回顾性干预研究。评估数据包括人口统计学、临床表现、影像学特征、手术技术、组织病理学、辅助治疗方式、并发症和疗效:共有 13 名患者纳入分析。84.6%的患者(11/13)以外溢和可触及肿块为主诉。近一半的患者(46.1%,6/13)被误诊为泪管阻塞。本系列中的所有泪囊肿瘤在T1加权磁共振成像中均显示不均匀强化。术后,84.6%(11/13)的患者恢复良好,美观度极佳,平均随访 58.6 个月后无病变。两名患者在接受姑息性化疗时(41 个月和 96 个月的随访期)再次发生复发并死亡:结论:内窥镜辅助下的改良韦伯-弗格森手术方法能有效提高泪囊肿瘤的可视性和可及性,并能将肿瘤扩展到邻近组织。
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来源期刊
Current Eye Research
Current Eye Research 医学-眼科学
CiteScore
4.60
自引率
0.00%
发文量
163
审稿时长
12 months
期刊介绍: The principal aim of Current Eye Research is to provide rapid publication of full papers, short communications and mini-reviews, all high quality. Current Eye Research publishes articles encompassing all the areas of eye research. Subject areas include the following: clinical research, anatomy, physiology, biophysics, biochemistry, pharmacology, developmental biology, microbiology and immunology.
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