The Impact of Oxidative Stress on Pregnancy. The Neglected Role of Alcohol Misuse.

Q2 Medicine Clinica Terapeutica Pub Date : 2024-01-01 DOI:10.7417/CT.2024.5033
A D'Angelo, M Peracchini, A Agostini, C Di Matteo, M Fiore, M Ceccanti, M Vitali, M P Messina
{"title":"The Impact of Oxidative Stress on Pregnancy. The Neglected Role of Alcohol Misuse.","authors":"A D'Angelo, M Peracchini, A Agostini, C Di Matteo, M Fiore, M Ceccanti, M Vitali, M P Messina","doi":"10.7417/CT.2024.5033","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Oxygen is essential for human life. However, it could cause damaging effects on biological systems causing oxidative stress. Oxidative stress defined as \"an alteration in the pro-oxidant-antioxidant balance in favor of the former that leads to potential damage\" is characterized by the release of Reactive Oxygen Species (ROS). Oxidative stress is now recognized to play a central role in the pathophysiology of many different disorders, including complications of pregnancy such as placental pathology, PreEclampsia (PE), Intrauterine Growth Restriction (IUGR), gestational diabetes, and miscarriage. This narrative review aims to summarize pieces of evidence about the role of oxidative stress in the pathophysiology of the main obstetric complications with par-ticular interest in the neglected role of alcohol abuse.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinica Terapeutica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7417/CT.2024.5033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Abstract: Oxygen is essential for human life. However, it could cause damaging effects on biological systems causing oxidative stress. Oxidative stress defined as "an alteration in the pro-oxidant-antioxidant balance in favor of the former that leads to potential damage" is characterized by the release of Reactive Oxygen Species (ROS). Oxidative stress is now recognized to play a central role in the pathophysiology of many different disorders, including complications of pregnancy such as placental pathology, PreEclampsia (PE), Intrauterine Growth Restriction (IUGR), gestational diabetes, and miscarriage. This narrative review aims to summarize pieces of evidence about the role of oxidative stress in the pathophysiology of the main obstetric complications with par-ticular interest in the neglected role of alcohol abuse.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
氧化应激对妊娠的影响。被忽视的酗酒问题。
摘要:氧气是人类生命的必需品。然而,氧气会对生物系统造成破坏性影响,导致氧化应激。氧化应激被定义为 "有利于前者而导致潜在损害的促氧化-抗氧化平衡的改变",其特点是释放活性氧(ROS)。氧化应激目前被认为在许多不同疾病的病理生理学中起着核心作用,包括妊娠并发症,如胎盘病理学、子痫前期(PE)、宫内生长受限(IUGR)、妊娠糖尿病和流产。这篇叙述性综述旨在总结氧化应激在主要产科并发症的病理生理学中作用的证据,尤其关注被忽视的酗酒问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Clinica Terapeutica
Clinica Terapeutica PHARMACOLOGY & PHARMACY-
CiteScore
2.50
自引率
0.00%
发文量
124
审稿时长
6-12 weeks
期刊介绍: La Clinica Terapeutica è una rivista di Clinica e Terapia in Medicina e Chirurgia, fondata nel 1951 dal Prof. Mariano Messini (1901-1980), Direttore dell''Istituto di Idrologia Medica dell''Università di Roma “La Sapienza”. La rivista è pubblicata come “periodico bimestrale” dalla Società Editrice Universo, casa editrice fondata nel 1945 dal Comm. Luigi Pellino. La Clinica Terapeutica è indicizzata su MEDLINE, INDEX MEDICUS, EMBASE/Excerpta Medica.
期刊最新文献
A denigration curve to delineate the spread of communication about obstetric staff errors in Italy and its practical application. An Anomalous Origin of the Accessory Splenic Artery and its Significance in Surgical and Radiological Contexts: A Case Report. Case of tracheal rupture after endotracheal intubation: clinical risk management and medico-legal considerations. Diagnostic performance of 3.0 Tesla diffusion tensor imaging in the assessment of brain stem glioma grading. Eggshell membrane as a regenerative material in alveolar bone grafting in combination with advanced platelet rich fibrin.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1