[Circulatory support with venovenous ECMO in a patient with reperfusion pulmonary edema after pulmonary artery thromboendarterectomy].

Emmanuel A Lazcano-Díaz, Uriel Encarnación-Martínez, Cristhian J Gaytán-García, Daniel Manzur-Sandoval, Francisco J González-Ruiz, Edgar García-Cruz, Ángel Ramos-Enríquez, Luis E Santos-Martínez, Luis A Cota-Apodaca, Benjamín I Hernández-Mejía, Dania E Escamilla-Ríos, Gustavo Rojas-Velasco
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Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a subtype of pulmonary hypertension characterized by the obstruction of pulmonary arteries secondary to chronic thromboembolism. Pulmonary thromboendarterectomy surgery (PTE) is the main treatment for patients with CTEPH, as it removes the chronic thrombi from the pulmonary arteries. Pulmonary reperfusion syndrome is a common complication of the surgery, which involves the development of pulmonary edema in the area where blood perfusion improves after the surgery. The incidence of this syndrome varies from 8 to 91% depending on the criteria used for diagnosis, and it is one of the most serious complications of pulmonary thromboendarterectomy. In such cases, circulatory support with extracorporeal membrane oxygenation (ECMO) has become a valuable therapeutic modality. We present the case of a 60-year-old woman with a history of acute pulmonary embolism due to deep vein thrombosis of the right pelvic limb who was diagnosed later with CTEPH who was admitted for scheduled surgical treatment involving bilateral PTE. However, during the immediate postoperative period, she developed cardiogenic shock and refractory hypoxemia secondary to pulmonary reperfusion syndrome following the surgical procedure. As a result, she required veno-venous ECMO circulatory support for 6 days, leading to resolution of the pulmonary condition and clinical improvement.

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[肺动脉血栓内膜切除术后再灌注肺水肿患者的静脉 ECMO 循环支持]。
慢性血栓栓塞性肺动脉高压(CTEPH)是肺动脉高压的一种亚型,其特点是继发于慢性血栓栓塞的肺动脉阻塞。肺血栓内膜剥脱术(PTE)是治疗 CTEPH 患者的主要方法,因为它可以清除肺动脉中的慢性血栓。肺再灌注综合征是手术的常见并发症,包括术后血液灌注改善的区域出现肺水肿。根据不同的诊断标准,这种综合征的发生率从 8% 到 91% 不等,是肺血栓内膜切除术最严重的并发症之一。在这种情况下,体外膜肺氧合(ECMO)循环支持已成为一种重要的治疗方式。我们介绍了一例 60 岁女性患者的病例,她曾因右侧盆腔肢体深静脉血栓形成导致急性肺栓塞,后被诊断为 CTEPH,入院接受双侧 PTE 手术治疗。然而,术后不久,她因手术后肺再灌注综合征而出现心源性休克和难治性低氧血症。因此,她需要静脉-静脉 ECMO 循环支持 6 天,从而缓解了肺部状况并改善了临床症状。
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