Ship collision accidents occur frequently and developing rapid prediction methods for structural crashworthiness analysis is of crucial importance in the design phase. This paper proposed a new analytical method to rapidly evaluate side structural responses impacted by a rigid raked bow in right-angle ship collisions with large indentation. Numerical simulations were carried out to help identify and understand the mechanisms of structural deformation of primary structural members. The side structure is divided into different key components and a new analytical model for evaluating the hull shell plating and stiffeners under large indentation subjected to lateral impact was developed. The model considered the shell plating deformation in three different phases, denting, ruptured and tearing phase. Different formulas were derived to cover the analysis from minor deflection to large indentation. Combined with other existing formulas for stiffened decks under in-plane loads, an integrated method was proposed to predict the total resistance and energy dissipation of the side structure. The newly developed method innovatively considered the coupling effects and interactions between various structural members in the collision analysis by dynamically correcting some parameters theoretically. The newly developed method was verified against numerical simulations of full-scale ship collisions through five typical scenarios and good accuracy was achieved. The newly developed method is valuable for use in the preliminary design phase, especially for severe collision scenarios.