Evaluation of clinical parallel workflow in online adaptive MR-guided Radiotherapy: A detailed assessment of treatment session times

Claudio Votta , Sara Iacovone , Gabriele Turco , Valerio Carrozzo , Marica Vagni , Aurora Scalia , Giuditta Chiloiro , Guenda Meffe , Matteo Nardini , Giulia Panza , Lorenzo Placidi , Angela Romano , Patrizia Cornacchione , Maria Antonietta Gambacorta , Luca Boldrini
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Abstract

Introduction

Advancements in MRI-guided radiotherapy (MRgRT) enable clinical parallel workflows (CPW) for online adaptive planning (oART), allowing medical physicists (MPs), physicians (MDs), and radiation therapists (RTTs) to perform their tasks simultaneously. This study evaluates the impact of this upgrade on the total treatment time by analyzing each step of the current 0.35T-MRgRT workflow.

Methods

The time process of the workflow steps for 254 treatment fractions in 0.35 MRgRT was examined. Patients have been grouped based on disease site, breathing modality (BM) (BHI or FB), and fractionation (stereotactic body RT [SBRT] or standard fractionated long course [LC]). The time spent for the following workflow steps in Adaptive Treatment (ADP) was analyzed: Patient Setup Time (PSt), MRI Acquisition and Matching (MRt), MR Re-contouring Time (RCt), Re-Planning Time (RPt), Treatment Delivery Time (TDt). Also analyzed was the timing of treatments that followed a Simple workflow (SMP), without the online re-planning (PSt + MRt + TDt.).

Results

The time analysis revealed that the ADP workflow (median: 34 min) is significantly (p < 0.05) longer than the SMP workflow (19 min). The time required for ADP treatments is significantly influenced by TDt, constituting 40 % of the total time. The oART steps (RCt + RPt) took 11 min (median), representing 27 % of the entire procedure. Overall, 79.2 % of oART fractions were completed in less than 45 min, and 30.6 % were completed in less than 30 min.

Conclusion

This preliminary analysis, along with the comparative assessment against existing literature, underscores the potential of CPW to diminish the overall treatment duration in MRgRT-oART. Additionally, it suggests the potential for CPW to promote a more integrated multidisciplinary approach in the execution of oART.

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评估在线自适应磁共振引导放疗的临床并行工作流程:治疗疗程时间的详细评估
导言:磁共振成像引导放射治疗(MRgRT)的先进技术实现了在线自适应计划(oART)的临床并行工作流(CPW),使医学物理师(MP)、内科医生(MD)和放射治疗师(RTT)能够同时完成他们的任务。本研究通过分析当前 0.35T MRgRT 工作流程的每个步骤,评估了这一升级对总治疗时间的影响。根据疾病部位、呼吸方式(BM)(BHI 或 FB)和分段(立体定向体部 RT [SBRT] 或标准分段长程 RT [LC])对患者进行分组。对自适应治疗(ADP)中以下工作流程步骤所花费的时间进行了分析:患者设置时间 (PSt)、核磁共振成像采集和匹配时间 (MRt)、核磁共振成像重新构图时间 (RCt)、重新规划时间 (RPt)、治疗实施时间 (TDt)。结果时间分析表明,ADP 工作流程(中位数:34 分钟)明显(p < 0.05)长于 SMP 工作流程(19 分钟)。ADP 处理所需时间受 TDt 影响很大,占总时间的 40%。oART 步骤(RCt + RPt)耗时 11 分钟(中位数),占整个流程的 27%。总体而言,79.2% 的 oART 分段在 45 分钟内完成,30.6% 的分段在 30 分钟内完成。结论这项初步分析以及与现有文献的比较评估强调了 CPW 在缩短 MRgRT-oART 整体治疗时间方面的潜力。此外,它还表明 CPW 有可能促进在实施 oART 时采用更加综合的多学科方法。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
48
审稿时长
67 days
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