Efficacy of endoscopic decompression surgery for treatment of lumbar spinal stenosis

Dharam Persaud-Sharma , Chamara Gunaratne , Jay Talati , Will Philips , Akib Sohel , Andrew Blake , Terrie Vasilopoulos , Sanjeev Kumar
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Abstract

Background

The overall aim of this study was to assess the effectiveness of endoscopic decompression for outcomes in patients with lumbar spinal stenosis (LSS).

Methods

We conducted a retrospective cohort, single-institution study of n = 139 patients from 2019 to 2022 who underwent endoscopic decompression for LSS. The primary outcome was improvement of Oswestry Disability Index (ODI) between baseline and 12-month follow-up.

Results

In the present sample (n = 139) the average age was 57.6 years (SD = 17.4, with even distribution of men (49%) vs. women (51%). In patients with LSS, lumbar disc herniation was the most common diagnosis in 49 patients followed by lumbar radiculopathy in 25 patients. Lumbar radicular pain was the 3rd most common diagnosis in 21 patients with all other diagnosis listed in Table S1. There was a significant improvement (i.e., decrease) in ODI following endoscopic decompression (mean change: −8.3, 95% CI: −9.4, −7.2, P < 0.001, Fig. 1). Prior lumbar spine surgery (P = 0.048), BMI (P = 0.053), and age (P = 0.022) were associated with changes in ODI. Nearly half (47%) of the sample had prior lumbar spine surgery. Those with prior lumbar spine surgery (−7.5, 95% CI: −8.3, −6.6) showed less improvement than those without prior lumbar spine surgery (−9.1, 95% CI: −10.9, −7.2, Fig. 2). For BMI, 23% had normal BMI while 24% were overweight and 53% were obese. Patients with normal BMI (−10.3, 95% CI: −13.4, −7.2) showed greater improvements compared to overweight (−7.9, 95% CI: −9.4, −6.4) and obese (−7.6, 95% CI: −9.0, −6.3, Fig. 3) patients. Patients under 40 years old (−10.2, 95% CI: −13.6, −6.8) showed greater improvements in ODI compared to those 40 years and older (−7.8, 95% CI: −8.6, −6.8, Fig. 4).

Conclusions

In patients with lumbar spinal stenosis, endoscopic decompression was associated with reduced disability. Patients with no prior lumbar spine surgery, normal BMI, and who were under 40 years old showed greater improvements.

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内窥镜减压手术治疗腰椎管狭窄症的疗效
背景本研究的总体目标是评估内窥镜减压术对腰椎管狭窄症(LSS)患者疗效的影响。方法我们对2019年至2022年期间接受内窥镜减压术治疗LSS的139名患者进行了一项回顾性队列、单一机构研究。主要结果是基线和 12 个月随访期间 Oswestry 失能指数(ODI)的改善情况。结果在本样本(n = 139)中,平均年龄为 57.6 岁(SD = 17.4),男性(49%)和女性(51%)分布均匀。在腰椎间盘突出症患者中,最常见的诊断是腰椎间盘突出症(49 人),其次是腰椎病(25 人)。腰椎痛是第三大常见诊断,有 21 名患者,其他诊断见表 S1。内窥镜减压术后,ODI 有明显改善(即下降)(平均变化:-8.3,95% CI:-9.4,-7.2,P < 0.001,图 1)。之前的腰椎手术(P = 0.048)、体重指数(BMI)(P = 0.053)和年龄(P = 0.022)与 ODI 的变化有关。近一半的样本(47%)曾接受过腰椎手术。与未接受过腰椎手术的样本(-9.1,95% CI:-10.9,-7.2,图 2)相比,接受过腰椎手术的样本(-7.5,95% CI:-8.3,-6.6)的改善幅度较小。在体重指数方面,23%的患者体重指数正常,24%超重,53%肥胖。与超重(-7.9,95% CI:-9.4,-6.4)和肥胖(-7.6,95% CI:-9.0,-6.3,图 3)患者相比,体重指数正常(-10.3,95% CI:-13.4,-7.2)患者的病情改善幅度更大。与 40 岁及以上患者(-7.8,95% CI:-8.6,-6.8,图 4)相比,40 岁以下患者(-10.2,95% CI:-13.6,-6.8)的 ODI 改善幅度更大。既往未接受过腰椎手术、体重指数正常且年龄在40岁以下的患者的病情改善程度更大。
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