UpFront

IF 2.4 Q3 GASTROENTEROLOGY & HEPATOLOGY Frontline Gastroenterology Pub Date : 2024-03-01 DOI:10.1136/flgastro-2024-102659
R Mark Beattie
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Abstract

We (mostly) think of abnormal serum amylase as being elevated. In this issue, Jalal and colleagues report a systematic review of the conditions associated with low serum amylase. The authors found 19 studies reporting 15 097 patients. The main conditions associated with low serum amylase were diabetes mellitus, metabolic syndrome, chronic pancreatitis (CP), non-alcoholic fatty liver disease and obesity. Low serum amylase showed a high specificity (94%) with low sensitivity (38.7%–59%) in diagnosing CP. The clinical implications are of interest. The authors suggest low amylase can be part of a metabolic process making it a useful metabolic marker in cases like obesity, metabolic syndrome and diabetes mellitus. It can be used as an exocrine marker and trigger investigation for pancreatic exocrine insufficiency. (See page 153) Chronic abdominal pain is common in inflammatory bowel disease (IBD) and not always straightforward to manage. In this issue, Baille and colleagues present a practical guide. The authors start by reviewing pain pathways (see figure 1). It is important to …
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我们(通常)认为血清淀粉酶异常就是升高。在本期杂志中,Jalal 及其同事对与血清淀粉酶偏低有关的情况进行了系统回顾。作者发现有 19 项研究报告了 15 097 名患者。与低血清淀粉酶相关的主要疾病有糖尿病、代谢综合征、慢性胰腺炎(CP)、非酒精性脂肪肝和肥胖症。在诊断慢性胰腺炎方面,低血清淀粉酶的特异性较高(94%),而敏感性较低(38.7%-59%)。其临床意义值得关注。作者认为,低淀粉酶可能是代谢过程的一部分,因此在肥胖、代谢综合征和糖尿病等病例中是一种有用的代谢标志物。淀粉酶可作为外分泌标志物,引发胰腺外分泌功能不全的检查。(见第 153 页)慢性腹痛是炎症性肠病(IBD)的常见症状,但并不总是可以直接控制。在本期中,Baille 及其同事提供了一份实用指南。作者首先回顾了疼痛的途径(见图 1)。重要的是...
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来源期刊
Frontline Gastroenterology
Frontline Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.70
自引率
11.50%
发文量
93
期刊介绍: Frontline Gastroenterology publishes articles that accelerate adoption of innovative and best practice in the fields of gastroenterology and hepatology. Frontline Gastroenterology is especially interested in articles on multidisciplinary research and care, focusing on both retrospective assessments of novel models of care as well as putative future directions of best practice. Specifically Frontline Gastroenterology publishes articles in the domains of clinical quality, patient experience, service provision and medical education.
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