Very low levels of physical activity among a broad group of patients hospitalized following hip fracture: A prospective cohort study (the HIP-ME-UP cohort study)

Maria Swennergren Hansen, Morten Tange Kristensen, Camilla Kampp Zilmer, Anja L Berger, Jeanette Wassar Kirk, Kira Marie Skibdal, Thomas Kallemose, Thomas Bandholm, Mette Merete Pedersen
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Abstract

Objectives: The evidence supports early and intensive mobilization and physical activity for hospitalized patients following a hip fracture. Since bedrest and inactivity during acute care are potentially fatal, we need updated knowledge of levels of physical activity in a diverse clinical population. Therefore, the objective was to determine levels of physical activity among a broad representation of patients hospitalized following hip fracture, and secondly to explore the association with 30-day post-discharge readmission, and mortality. Design: Prospective cohort study Setting: Data were collected at two university hospitals in the Capital Region of Denmark from March to June 2023. Participants: Patients hospitalized following hip fracture. Main outcome measures: 24-hr upright time (time standing and walking) was measured from inclusion (post-operative day (POD) 1-3) to discharge using a thigh-worn accelerometer. Readmission and mortality were verified by electronic patient records. Results: 101 patients (62 women) with a mean (SD) age of 79.9 (8.4) years were included. The median (IQR) 24-hr upright time on POD2-6 ranged from 15 (6.9:31.0) to a maximum of 34 (16:67) mins. Patients with cognitive impairment had less upright time than patients without. Post-surgery length of stay was a median of 7 (5:8) days. 25% of the patients were readmitted or had emergency ward referrals and 3% died within 30 days of discharge (no clear association with upright time). Conclusions: Physical activity seems extremely low among a broad representation of patients within the first week following a hip fracture but was not found to influence readmissions. Considering the strong evidence supporting physical activity during acute hospitalization, the low activity level in these patients calls for action. Clinicaltrials.gov-identifier: NCT05756517
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髋部骨折后住院的广大患者中,体育锻炼水平极低:前瞻性队列研究(HIP-ME-UP 队列研究)
目标:有证据表明,髋部骨折后的住院患者应尽早加强活动和体育锻炼。由于在急性期卧床休息和不活动可能会致命,我们需要对不同临床人群的体力活动水平有最新的了解。因此,我们的目标是确定髋部骨折住院患者的体力活动水平,其次探讨体力活动与出院后 30 天再入院及死亡率的关系。设计:前瞻性队列研究前瞻性队列研究 设定:从 2023 年 3 月到 6 月在丹麦首都地区的两所大学医院收集数据。参与者:髋部骨折住院患者:髋部骨折住院患者。主要结果指标:使用佩戴在大腿上的加速度计测量患者从入院(术后第 1-3 天)到出院的 24 小时直立时间(站立和行走时间)。再入院和死亡率由电子病历核实。结果共纳入 101 名患者(62 名女性),平均(标清)年龄为 79.9 (8.4) 岁。POD2-6 24 小时直立时间的中位数(IQR)从 15 分钟(6.9:31.0)到最长 34 分钟(16:67)不等。认知障碍患者的直立时间少于无认知障碍患者。手术后住院时间的中位数为 7 天(5:8)。25%的患者再次入院或转入急诊病房,3%的患者在出院后30天内死亡(与直立时间无明显关联)。结论在髋部骨折后的第一周内,大多数患者的体育锻炼量似乎极低,但并未发现体育锻炼会影响再次入院。考虑到支持急性住院期间进行体育锻炼的有力证据,这些患者的低活动水平需要我们采取行动。Clinicaltrials.gov-identifier:NCT05756517
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