The use of dermal templates in dermato-surgery and patient perspectives

IF 2.3 Q2 DERMATOLOGY Dermatology Reports Pub Date : 2024-02-15 DOI:10.4081/dr.2024.9941
Serena Morsia, A. Paganelli, Alessandra Acciardi, Antonio Alma, Cristina Bertoli, Camilla Reggiani, F. Garbarino, C. Fiorentini, B. Ferrari, M. Francomano, Cristina Magnoni
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Abstract

Acellular dermal matrices, currently represent a useful reconstructive method in onco-dermatologic surgery. Nevertheless, they have some limitations, especially in terms of costs and outpatient post-operative wound care. While some studies on their cost-to-benefit ratio in breast surgery have already been issued, evidence is currently lacking in onco-dermatological surgery. The aim of this study was to evaluate the clinical outcomes perceived by patients who had undergone onco-dermatologic surgery in which either acellular dermal matrices or skin grafts had been used as reconstructive methods. A study population of 150 patients was identified retrospectively and patients’ degree of satisfaction was assessed through the Global Aesthetic Improvement Scale and the Patient Scar Scale Questionnaire. Despite similar scores among the study groups, slightly better results were appreciable after single-stage grafting. However, to what extent these variations really represent a significant difference from a clinical point of view remains to be determined. Moreover, other potential bias in the interpretation of our results may reside in differences in terms of age, body location and baseline tumor size among the study groups. Therefore, further research is needed.
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在皮肤外科手术中使用皮肤模板及患者的观点
细胞真皮基质是目前皮肤科手术中一种有用的重建方法。不过,这种方法也有一些局限性,尤其是在成本和门诊术后伤口护理方面。虽然已经有一些关于其在乳房手术中成本效益比的研究,但目前在皮肤科手术中还缺乏证据。本研究的目的是评估接受过人造皮肤基质或植皮作为重建方法的皮肤外科手术的患者所感受到的临床效果。研究人员通过回顾性研究确定了 150 名患者,并通过全球美学改善量表和患者疤痕量表问卷评估了患者的满意度。尽管各研究组的得分相近,但单段植皮术的效果略好。不过,从临床角度来看,这些差异在多大程度上真正代表了显著差异,还有待确定。此外,研究组之间在年龄、身体位置和肿瘤基线大小方面的差异也可能对我们的结果产生解释上的偏差。因此,还需要进一步的研究。
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来源期刊
Dermatology Reports
Dermatology Reports DERMATOLOGY-
CiteScore
1.40
自引率
0.00%
发文量
74
审稿时长
10 weeks
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