ROUTE OF ADMINISTRATION OF NANOPARTICLES COMBATING A RESISTANT BACTERIUM.

Asif Naeem, Z. N. Qaisrani, Shazia, A. Noor, Imran Hussain, Asif Raheem
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Abstract

In the middle of the late century, the concept of medicine has been reshaped and reformed by the discovery of antibiotics. Untreatable infectious diseases have become treatable, However, with time microbes adapt to resist the antibiotic treatments due to their enormous adaptive ability. Therefore, new antibiotics were required to combat these resistant bacteria. But the enormous adaptive ability of bacteria has turned the next generation of antibiotics obsolete. Thus, Nanoparticles play a crucial role due to their antibacterial activity. Besides, these can act as carriers for various antibiotics to increase their efficiency against superbugs. The current review provides an in-depth overview of nanoparticles, their biosynthesis, antibacterial activity, and synergistic effects with various antibiotics.
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纳米粒子的给药途径,以对抗耐药细菌。
本世纪中叶,抗生素的发现重塑和改革了医学的概念。然而,随着时间的推移,微生物因其巨大的适应能力而对抗生素治疗产生了抗药性。因此,需要新的抗生素来对付这些抗药性细菌。但是,细菌的巨大适应能力使新一代抗生素变得过时。因此,纳米粒子因其抗菌活性而发挥了至关重要的作用。此外,纳米颗粒还可以作为各种抗生素的载体,提高它们对付超级细菌的效率。本综述深入概述了纳米粒子、其生物合成、抗菌活性以及与各种抗生素的协同作用。
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