Isolated dextrocardia and rheumatoid arthritis with mitral stenosis with pulmonary hypertension with atrial fibrillation: A rare association

K. C. Shashidhara, Sai Surya Chukkapalli, Amara Charitha Duggirala, Sai Sisir Madala, Preeti Prakash Prabhu
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Abstract

This case presents a rare occurrence of rheumatoid arthritis (RA) in a 50-year-old woman with concurrent mitral valvular disease and dextrocardia. Diagnosed with seropositive RA 5 years earlier, the patient exhibited fever, cough, and progressive dyspnea. Clinical examination revealed irregular tachycardia, elevated jugular venous pressure, and signs of heart failure. Laboratory results confirmed seropositive RA, anemia, and elevated inflammatory markers. Electrocardiogram and echocardiogram indicated dextrocardia, atrial fibrillation, and moderate mitral stenosis. This case highlights the unusual association of RA with valvular heart disease and the added complexity of dextrocardia. Recognizing diverse cardiac manifestations in RA is crucial, contributing to the growing evidence linking autoimmune disorders to cardiovascular complications. Further research is essential to understand the intricate relationship between RA and unique cardiac abnormalities.
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孤立性右心室和类风湿性关节炎伴二尖瓣狭窄、肺动脉高压和心房颤动:罕见的关联
本病例是一名 50 岁女性罕见的类风湿性关节炎(RA)病例,患者同时患有二尖瓣疾病和右心室突出。患者 5 年前被诊断为血清阳性 RA,表现为发热、咳嗽和进行性呼吸困难。临床检查发现患者有不规则心动过速、颈静脉压升高和心力衰竭症状。实验室检查结果证实,患者的血清 RA 阳性、贫血和炎症指标升高。心电图和超声心动图显示有右心室传导阻滞、心房颤动和二尖瓣中度狭窄。该病例凸显了 RA 与瓣膜性心脏病的不寻常关联以及右心室增大的复杂性。认识到RA的多种心脏表现至关重要,这有助于增加自身免疫性疾病与心血管并发症相关联的证据。要了解 RA 与独特的心脏异常之间错综复杂的关系,进一步的研究必不可少。
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