Yang Xue, An Yan, Sara Amirpour Amraii, S. Goorani
{"title":"Determination of Cytotoxicity and Anti-Human Lung Cancer Properties of Silver Nanoparticles Green-Formulated by Foeniculum vulgare Extract","authors":"Yang Xue, An Yan, Sara Amirpour Amraii, S. Goorani","doi":"10.1166/jbn.2024.3775","DOIUrl":null,"url":null,"abstract":"Foeniculum vulgare is a plant with many therapeutic effects. In the current research, silver nanoparticles were synthesized by the Foeniculum vulgare extract. The properties of silver nanoparticles against lung cancer cell lines i.e., H69, COR-L47, DMS53, DMS79, NCI-H69/LX20,\n SHP-77, NCI-H69/CPR, and NCI-H69/LX4 were evaluated. The green-formulated silver nanoparticles were characterized by various tests such as FE-SEM, EDX, FT-IR, and XRD. The FE-SEM findings prove spherical morphology for the AgNPs with the size of 19.34 to 47.93 nm. The IC50 of the silver nanoparticles\n was 426, 547, 370, 377, 500, 384, 329, and 330 against H69, COR-L47, DMS53, DMS79, NCI-H69/LX20, SHP-77, NCI-H69/CPR, and NCI-H69/LX4, respectively. After doing the studies of clinical trial, the current nanoparticles may be used as an anti-lung cancer supplement in humans.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":"364 ","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1166/jbn.2024.3775","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
Foeniculum vulgare is a plant with many therapeutic effects. In the current research, silver nanoparticles were synthesized by the Foeniculum vulgare extract. The properties of silver nanoparticles against lung cancer cell lines i.e., H69, COR-L47, DMS53, DMS79, NCI-H69/LX20,
SHP-77, NCI-H69/CPR, and NCI-H69/LX4 were evaluated. The green-formulated silver nanoparticles were characterized by various tests such as FE-SEM, EDX, FT-IR, and XRD. The FE-SEM findings prove spherical morphology for the AgNPs with the size of 19.34 to 47.93 nm. The IC50 of the silver nanoparticles
was 426, 547, 370, 377, 500, 384, 329, and 330 against H69, COR-L47, DMS53, DMS79, NCI-H69/LX20, SHP-77, NCI-H69/CPR, and NCI-H69/LX4, respectively. After doing the studies of clinical trial, the current nanoparticles may be used as an anti-lung cancer supplement in humans.
期刊介绍：
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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