Poūmės kombinuotos nugaros smegenų degeneracijos, sukeltos diazoto monoksido („linksminančių dujų”) vartojimo, klinikinio atvejo aprašymas

J. Guk, J. Valančienė, A. Klimašauskienė
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Abstract

Although nitrous oxide (N2O) has long been used as an anesthetic, it’s use as a recreational drug has recently increased. As N2O abuse is associated with a number of adverse health effects, it has become a significant public health issue. Chronic abuse can lead to a number of neurological complications, most commonly related to functional vitamin B12 deficiency. One of the most encountered forms of N2O neurotoxicity is a subacute combined degeneration, which can cause permanent neurological damage. The medical community should therefore be aware of the increasing scale of recreational N2O exposure and the possible complications of this drug abuse. Early recognition and treatment of N2O toxicity are crucial. We present the case of an 18-year-old male who was diagnosed with subacute combined spinal cord degeneration related to N2O abuse.
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使用一氧化二氮("笑气")导致亚急性合并脊髓变性的临床病例报告
尽管一氧化二氮(N2O)长期以来一直被用作麻醉剂,但近来它作为一种娱乐性药物的使用却越来越多。由于一氧化二氮的滥用与一系列不良健康影响有关,它已成为一个重要的公共卫生问题。长期滥用可导致多种神经系统并发症,最常见的是功能性维生素 B12 缺乏症。亚急性联合变性是最常见的 N2O 神经中毒形式之一,可造成永久性神经损伤。因此,医学界应该意识到娱乐性一氧化二氮接触的规模越来越大,以及这种药物滥用可能带来的并发症。及早识别和治疗一氧化二氮中毒至关重要。我们介绍了一个 18 岁男性的病例,他被诊断出患有与一氧化二氮滥用有关的亚急性合并脊髓变性。
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