TEAR FILM CHANGES FOLLOWING PHACOEMULSIFICATION SURGERY IN PRIMARY EYE CARE CENTER

TRI WAHYU
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Abstract

Abstract Introduction & Objectives : Dry eye disease (DED) is one of the most commonly encountered problem in daily ophthalmology practice. One of many risk factors for DED is cataract surgery. Cataract surgery is known to modify tear film and ocular surface through corneal incision and ocular toxicity of peri- and postoperative medications. The aim of this study is to analyze tear film before and after phacoemulsification in primary eye care facility by measuring tear break-up time (TBUT), fluorescein staining, Schirmer I test (ST-I), and ocular surface disease index (OSDI) score. Methods : This was a longitudinal observational study with prospective cohort design, which included patients diagnosed with senile cataract and underwent uncomplicated phacoemulsification surgery at primary eye care center Sawangan Eye Clinic within period of June to December 2022. Friedman, Wilcoxon, and Cochran tests were used to analyze the data. Results : Thirty nine eyes from 39 patients met the inclusion criteria and were followed up to 3-month postoperatively. Mean age of the patients was 61.1±10.54 years, which consited of 53.8% males and 46.2% females. Mean preoperative OSDI score, corneal staining, TBUT, and ST-I were 24.94±10.24, 1.38±1.99, 2.94±2.17, and 15.46±8.80 respectively; while 3-month postoperative, these parameters’ means were 11.22±13.15 (p=0.0001), 1.38±2.56 (p=0.118), 3.13±1.79 (p=0.192), and 13.31±9.45 (p=0.006) respectively. OSDI was the only parameter which showed statistically significant changes from preoperative to postoperative follow ups (p<0.05). Conclusion : Phacoemulsification did not alter corneal staining and TBUT significantly after 3 months postoperatively, even though both of these parameters' preoperative value were already lower; yet OSDI score improved over time after surgery.
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基层眼科中心进行超声乳化手术后泪膜的变化
摘要 简介与目的:干眼症(DED)是眼科日常工作中最常遇到的问题之一。白内障手术是导致干眼症的众多危险因素之一。众所周知,白内障手术会通过角膜切口以及围手术期和术后药物的眼部毒性改变泪膜和眼表。本研究旨在通过测量泪液破裂时间(TBUT)、荧光素染色、Schirmer I 测试(ST-I)和眼表疾病指数(OSDI)评分,分析基层眼科医疗机构进行超声乳化手术前后的泪膜情况。方法:这是一项采用前瞻性队列设计的纵向观察研究,研究对象包括 2022 年 6 月至 12 月期间在初级眼科医疗中心泽望安眼科诊所确诊为老年性白内障并接受无并发症超声乳化手术的患者。数据分析采用弗里德曼检验、Wilcoxon 检验和 Cochran 检验。结果:39 名患者的 39 只眼睛符合纳入标准,并接受了术后 3 个月的随访。患者的平均年龄为(61.1±10.54)岁,其中男性占 53.8%,女性占 46.2%。术前OSDI评分、角膜染色、TBUT和ST-I的平均值分别为(24.94±10.24)、(1.38±1.99)、(2.94±2.17)和(15.46±8.80);术后3个月,这些参数的平均值分别为(11.22±13.15)(P=0.0001)、(1.38±2.56)(P=0.118)、(3.13±1.79)(P=0.192)和(13.31±9.45)(P=0.006)。OSDI是唯一一个从术前到术后随访均有显著统计学变化的参数(p<0.05)。结论:尽管术前的角膜染色和TBUT值已经较低,但术后3个月后,脉冲乳化术并没有显著改变这两项参数;但术后OSDI评分随着时间的推移有所提高。
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