Tympanostomy tube placement for intractable Meniere's disease in the elderly.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 Epub Date: 2024-02-20 DOI:10.1080/00016489.2024.2312231
Wenting Deng, Yuebo Chen, Hao Xiong, Yongkang Ou
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Abstract

Background: The treatment of refractory elderly Meniere's disease is a challenge.

Aim: To investigate the efficacy of tympanostomy tube placement in elderly patients with Meniere's disease.

Methods: 31 patients over 60 years old with Meniere's disease who had failed medical treatment and underwent tympanostomy tube placement. Vertigo control, hearing level, tinnitus, and ear fullness were recorded and analyzed preoperatively and postoperatively.

Results: All patients completed a 6-month follow-up. At 6 months postoperatively,complete control, substantial control and limited control of vertigo were achieved in 10 (32%), 13 (42%), and 6 (19%) patients respectively. Two patients (6%) reported no substantial improvement. Twelve patients completed a 2-year follow-up. At 2 years postoperatively, complete control, substantial control and limited control of vertigo were achieved in 3 (25%), 5 (42%), and 1 (8%) patients respectively. Three (25%) patients showed no significant improvement in vertigo. The majority of patients reported significant improvement in the functional level scale, the Dizziness Handicap Inventory scores, and ear fullness at 6 months and 2 years postoperatively.

Conclusions and significance: Tympanostomy tube placement may reduce vertigo attacks and improved the quality of life in elderly patients with Meniere's disease.

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鼓室造口术置管术治疗老年人顽固性梅尼埃病。
背景:治疗难治性老年梅尼埃病是一项挑战:目的:探讨鼓室造口术置管术对老年美尼尔病患者的疗效。方法:31 名 60 岁以上的美尼尔病患者经药物治疗无效后接受鼓室造口术置管术。结果:所有患者均完成了 6 个月的随访:所有患者均完成了为期 6 个月的随访。术后 6 个月,分别有 10 名(32%)、13 名(42%)和 6 名(19%)患者的眩晕得到完全控制、基本控制和有限控制。两名患者(6%)称没有实质性改善。12 名患者完成了为期 2 年的随访。术后 2 年,分别有 3 名(25%)、5 名(42%)和 1 名(8%)患者的眩晕症状得到完全控制、基本控制和有限控制。3名(25%)患者的眩晕症状没有明显改善。大多数患者在术后 6 个月和 2 年时,功能水平量表、头晕障碍量表评分和耳部饱胀感均有明显改善:鼓室造口术置管术可减少老年梅尼埃病患者的眩晕发作,提高其生活质量。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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