Prevalence and underreporting of immunization errors in childhood vaccination: results of a household survey.

Revista da Escola de Enfermagem da U S P Pub Date : 2024-02-19 eCollection Date: 2024-01-01 DOI:10.1590/1980-220X-REEUSP-2023-0253en
Stênio Henrique Oliveira, Brener Santos Silva, Lívia Maria Rezende Carvalho, Tarcísio Laerte Gontijo, Ione Carvalho Pinto, Eliete Albano de Azevedo Guimarães, Valéria Conceição de Oliveira
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Abstract

Objective: To investigate underreporting of immunization errors based on vaccination records from children under five years of age.

Method: An epidemiological, cross-sectional analytical study, carried out through a household survey with 453 children aged 6 months to 4 years in three municipalities in Minas Gerais in 2021. A descriptive analysis was carried out, and the prevalence of the error was calculated per 100 thousand doses applied between 2016 and 2021. The magnitude was estimated of the association between variables by prevalence and 95% Confidence Intervals (95%CI). To analyze underreporting, State reporting records were used.

Results: A prevalence of immunization errors was found to be 41.9/100,000 doses applied (95%CI:32.2 - 51.6). The highest prevalence occurred between 2020 (50.0/100,000 doses applied) and 2021 (78.6/100,000 doses applied). The most frequent error was an inadequate interval between vaccines (47.2%) associated with adsorbed diphtheria, tetanus and pertussis (DTP) vaccine (13.7/100,000) administration. Vaccination delay was related to immunization errors (7.55 95% CI:2.30 - 24.80), and the errors found were underreported.

Conclusion: The high prevalence of underreported errors points to a worrying scenario, highlighting the importance of preventive measures.

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儿童疫苗接种中免疫接种错误的发生率和漏报率:一项家庭调查的结果。
目的:根据五岁以下儿童的疫苗接种记录,调查免疫接种错误的漏报情况:根据五岁以下儿童的疫苗接种记录,调查免疫接种错误的漏报情况:一项流行病学横断面分析研究,于 2021 年在米纳斯吉拉斯州的三个城市对 453 名 6 个月至 4 岁的儿童进行了家庭调查。研究进行了描述性分析,并计算了 2016 年至 2021 年期间每 10 万剂量的错误发生率。通过流行率和 95% 置信区间 (95%CI) 估算变量之间的关联程度。为了分析漏报情况,使用了国家报告记录:免疫接种错误的发生率为 41.9/100,000(95%CI:32.2 - 51.6)。最高发生率出现在 2020 年(50.0/100,000 剂)和 2021 年(78.6/100,000 剂)之间。最常见的错误是与吸附白喉、破伤风和百日咳(DTP)疫苗(13.7/100,000)接种相关的疫苗接种间隔不足(47.2%)。疫苗接种延迟与免疫接种错误有关(7.55 95% CI:2.30-24.80),而且发现的错误报告不足:结论:漏报差错的发生率很高,情况令人担忧,这凸显了预防措施的重要性。
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