Ultrasound and antibodies — a potentially powerful combination for Alzheimer disease therapy

IF 28.2 1区 医学 Q1 CLINICAL NEUROLOGY Nature Reviews Neurology Pub Date : 2024-02-20 DOI:10.1038/s41582-024-00943-1
Jürgen Götz, Pranesh Padmanabhan
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Abstract

Success in a trial of low-intensity ultrasound combined with an amyloid-β antibody represents a major stride towards integrating pharmacological and nonpharmacological approaches to reduce the amyloid-β load in patients with mild Alzheimer disease. This trial also highlights the potential of therapeutic ultrasound modalities to combat neurodegenerative diseases.

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超声波和抗体--阿尔茨海默病治疗的潜在强效组合。
低强度超声波与淀粉样蛋白-β抗体相结合的试验取得成功,标志着在整合药物疗法和非药物疗法以减少轻度阿尔茨海默病患者的淀粉样蛋白-β负荷方面迈出了一大步。这项试验还凸显了超声治疗模式在防治神经退行性疾病方面的潜力。
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来源期刊
Nature Reviews Neurology
Nature Reviews Neurology 医学-临床神经学
CiteScore
29.90
自引率
0.80%
发文量
138
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.
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