Multimodality Appearances of Marginal Zone Lymphoma Masquerading as Cryptogenic Organizing Pneumonia-serial Chest Radiograph and High-resolution Computed Tomography Appearances: (¹⁸F) Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Staging Utility.

IF 0.4 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Indian Journal of Nuclear Medicine Pub Date : 2023-10-01 Epub Date: 2023-12-20 DOI:10.4103/ijnm.ijnm_83_23

Elizabeth Robinson, Ayah Nawwar, Julie Searle, Iain Lyburn

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Abstract

Marginal zone lymphoma (MZL) is a group of low-grade, indolent, non-Hodgkin lymphomas rarely manifesting in the lungs. A 46-year-old man presenting with shortness of breath and cough was investigated and treated over 10 months for an atypical pattern of lung disease in keeping with cryptogenic organizing pneumonia (COP). Initial lung biopsies were nondiagnostic - repeat sampling eventually showed MZL. Staging whole-body (¹⁸F) fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) demonstrated multisystem stage IV disease with intensely avid widespread pulmonary changes resembling COP. The case elegantly illustrates that pulmonary MZL can present insidiously masquerading as COP and shows the value of (¹⁸F) FDG PET/CT to stage extranodal MZL.

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伪装成隐源性组织性肺炎的边缘区淋巴瘤的多模态表现-胸部X光片和高分辨率计算机断层扫描表现：(18F)氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描的分期效用。

边缘区淋巴瘤（MZL）是一类低度、惰性、非霍奇金淋巴瘤，很少出现在肺部。一名 46 岁的男子因气短和咳嗽而接受了长达 10 个月的检查和治疗，其肺部疾病模式不典型，与隐源性组织化肺炎（COP）一致。最初的肺活检无法确诊--重复取样最终显示出 MZL。分期全身（18F）氟脱氧葡萄糖（FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）显示，该病为多系统疾病 IV 期，肺部广泛的强阳性改变与 COP 相似。该病例很好地说明了肺部MZL可隐匿地伪装成COP，并显示了(18F) FDG PET/CT对结节外MZL分期的价值。

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Indian Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

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