Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm.

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Tomography Pub Date : 2024-02-16 DOI:10.3390/tomography10020023

Davide Ippolito, Marco Porta, Cesare Maino, Luca Riva, Maria Ragusi, Teresa Giandola, Paolo Niccolò Franco, Cecilia Cangiotti, Davide Gandola, Andrea De Vito, Cammillo Talei Franzesi, Rocco Corso

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Abstract

Aim: To evaluate the dose reduction and image quality of low-dose, low-contrast media volume in computed tomography (CT) examinations reconstructed with the model-based iterative reconstruction (MBIR) algorithm in comparison with the hybrid iterative (HIR) one. Methods: We prospectively enrolled a total of 401 patients referred for cardiovascular CT, evaluated with a 256-MDCT scan with a low kVp (80 kVp) reconstructed with an MBIR (study group) or a standard HIR protocol (100 kVp-control group) after injection of a fixed dose of contrast medium volume. Vessel contrast enhancement and image noise were measured by placing the region of interest (ROI) in the left ventricle, ascending aorta; left, right and circumflex coronary arteries; main, right and left pulmonary arteries; aortic arch; and abdominal aorta. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were computed. Subjective image quality obtained by consensus was assessed by using a 4-point Likert scale. Radiation dose exposure was recorded. Results: HU values of the proximal tract of all coronary arteries; main, right and left pulmonary arteries; and of the aorta were significantly higher in the study group than in the control group (p < 0.05), while the noise was significantly lower (p < 0.05). SNR and CNR values in all anatomic districts were significantly higher in the study group (p < 0.05). MBIR subjective image quality was significantly higher than HIR in CCTA and CTPA protocols (p < 0.05). Radiation dose was significantly lower in the study group (p < 0.05). Conclusions: The MBIR algorithm combined with low-kVp can help reduce radiation dose exposure, reduce noise, and increase objective and subjective image quality.

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基于模型算法重建计算机断层扫描心血管成像中低剂量和低对比度介质容积方法的可行性。

目的：与混合迭代（HIR）算法相比，评估基于模型的迭代重建（MBIR）算法重建的计算机断层扫描（CT）检查中低剂量、低对比度介质容积的剂量降低情况和图像质量。研究方法我们对 401 名转诊的心血管 CT 患者进行了前瞻性研究，在注射固定剂量的造影剂后，使用 MBIR（研究组）或标准 HIR 方案（100 kVp-对照组）重建的低 kVp（80 kVp）256-MDCT 扫描进行评估。通过将感兴趣区（ROI）置于左心室、升主动脉；左、右和环冠状动脉；主、右和左肺动脉；主动脉弓和腹主动脉来测量血管对比度增强和图像噪声。计算信噪比（SNR）和对比度-信噪比（CNR）。采用 4 点李克特量表对共识获得的主观图像质量进行评估。记录辐射剂量。结果研究组所有冠状动脉近段、主肺动脉、右肺动脉和左肺动脉以及主动脉的 HU 值均显著高于对照组（P < 0.05），而噪声则显著低于对照组（P < 0.05）。研究组所有解剖区域的 SNR 和 CNR 值均明显高于对照组（P < 0.05）。在 CCTA 和 CTPA 方案中，MBIR 的主观图像质量明显高于 HIR（P < 0.05）。研究组的辐射剂量明显较低（P < 0.05）。结论MBIR 算法与低 kVp 相结合有助于减少辐射剂量暴露、降低噪音并提高客观和主观图像质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tomography Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.70

自引率

10.50%

发文量

222

期刊介绍： TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.