[Failure of poliomyelitis eradication campaign with oral vaccine: there's no vaccination without adherence].

Medecine tropicale et sante internationale Pub Date : 2023-11-16 eCollection Date: 2023-12-31 DOI:10.48327/mtsi.v3i4.2023.402
Bernard Seytre
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Abstract

Thirty-five years after its launch, the Global Polio Eradication Initiative has yet to reach its original goal of 2000. Not only is the wild type 1 polio virus still endemic in two countries, but a new outbreak due to viruses derived from the live attenuated virus used for the oral vaccine has been spreading since 2016. The National Immunization Days (NID), during which teams go door-to-door and attract children to be vaccinated, have provoked violent opposition particularly in Northern Nigeria and in the area of India, Pakistan, Afghanistan. In both regions, the same rumor has developed that the vaccine contains sterilizing products, in order to limit the Muslim population. The organizers of the campaign multiplied in vain the NIDs to overcome the resistance, but pockets of insufficiently vaccinated population have persisted. This has allowed the wild virus to remain endemic and the new outbreak of vaccine-derived viruses to progress. We can wonder what the campaign would have become if its organizers had taken the time to reflect and reorient their strategy to rely on the routine vaccination of the Expanded Program on Immunization that does not arouse such opposition.

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[使用口服疫苗根除脊髓灰质炎运动的失败:没有坚持就没有疫苗接种]。
全球根除脊髓灰质炎倡议发起 35 年后,仍未实现 2000 年的最初目标。不仅野生 1 型脊髓灰质炎病毒仍在两个国家流行,而且自 2016 年以来,由用于口服疫苗的减毒活疫苗衍生病毒引起的新疫情也在蔓延。在 "全国免疫日"(NID)期间,免疫接种小组挨家挨户吸引儿童接种疫苗,但却引发了暴力反对,尤其是在尼日利亚北部以及印度、巴基斯坦和阿富汗地区。在这两个地区,都出现了同样的谣言,说疫苗含有绝育产品,目的是限制穆斯林人口。运动的组织者徒劳地增加了 NIDs 以克服阻力,但接种不足的小块人口仍然存在。这使得野病毒继续流行,而疫苗衍生病毒的新爆发则不断进展。我们不禁要问,如果这场运动的组织者能够花时间进行反思,并重新调整战略,依靠扩大免疫计划的常规疫苗接种,而不会引起如此强烈的反对,那么这场运动会变成什么样呢?
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