MicroRNAs in Male Fertility.

DNA and cell biology Pub Date : 2024-03-01 Epub Date: 2024-02-23 DOI:10.1089/dna.2023.0314

Sedigheh Bahmyari, Seyyed Hossein Khatami, Sina Taghvimi, Sahar Rezaei Arablouydareh, Mortaza Taheri-Anganeh, Hojat Ghasemnejad-Berenji, Tooba Farazmand, Elahe Soltani Fard, Arezoo Solati, Ahmad Movahedpour, Hassan Ghasemi

{"title":"MicroRNAs in Male Fertility.","authors":"Sedigheh Bahmyari, Seyyed Hossein Khatami, Sina Taghvimi, Sahar Rezaei Arablouydareh, Mortaza Taheri-Anganeh, Hojat Ghasemnejad-Berenji, Tooba Farazmand, Elahe Soltani Fard, Arezoo Solati, Ahmad Movahedpour, Hassan Ghasemi","doi":"10.1089/dna.2023.0314","DOIUrl":null,"url":null,"abstract":"<p><p>Around 50% of all occurrences of infertility are attributable to the male factor, which is a significant global public health concern. There are numerous circumstances that might interfere with spermatogenesis and cause the body to produce abnormal sperm. While evaluating sperm, the count, the speed at which they migrate, and their appearance are the three primary characteristics that are analyzed. MicroRNAs, also known as miRNAs, are present in all physiological fluids and tissues. They participate in both physiological and pathological processes. Researches have demonstrated that the expression of microRNA genes differs in infertile men. These genes regulate spermatogenesis at various stages and in several male reproductive cells. Hence, microRNAs have the potential to act as useful indicators in the diagnosis and treatment of male infertility and other diseases affecting male reproduction. Despite this, additional research is necessary to determine the precise miRNA regulation mechanisms.</p>","PeriodicalId":93981,"journal":{"name":"DNA and cell biology","volume":" ","pages":"108-124"},"PeriodicalIF":0.0000,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"DNA and cell biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/dna.2023.0314","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/23 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Around 50% of all occurrences of infertility are attributable to the male factor, which is a significant global public health concern. There are numerous circumstances that might interfere with spermatogenesis and cause the body to produce abnormal sperm. While evaluating sperm, the count, the speed at which they migrate, and their appearance are the three primary characteristics that are analyzed. MicroRNAs, also known as miRNAs, are present in all physiological fluids and tissues. They participate in both physiological and pathological processes. Researches have demonstrated that the expression of microRNA genes differs in infertile men. These genes regulate spermatogenesis at various stages and in several male reproductive cells. Hence, microRNAs have the potential to act as useful indicators in the diagnosis and treatment of male infertility and other diseases affecting male reproduction. Despite this, additional research is necessary to determine the precise miRNA regulation mechanisms.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

男性生育能力中的微RNA。

在所有不孕不育症中，约有 50%是由于男性因素造成的，这是一个重大的全球公共卫生问题。有许多情况可能会干扰精子的生成，导致人体产生异常精子。在对精子进行评估时，要分析精子的数量、移动速度和外观这三个主要特征。微小核糖核酸（又称 miRNA）存在于所有生理液体和组织中。它们参与生理和病理过程。研究表明，不育男性体内的 microRNA 基因表达有所不同。这些基因在不同阶段和多个男性生殖细胞中调节精子的生成。因此，microRNA 有可能成为诊断和治疗男性不育和其他影响男性生殖的疾病的有用指标。尽管如此，要确定 miRNA 的精确调控机制，还需要进行更多的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

DNA and cell biology

自引率

0.00%

发文量