Correlation between sperm DNA fragmentation index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI: A cross-sectional study

Sunil K S, Sunil C V, Apoorva Jain
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Abstract

: During an evaluation of infertile men when all standard semen parameters are normal, a significant proportion of infertile men are found to have increased levels of DNA damage that may adversely affect fertility. To evaluate the correlation between sperm DNA Fragmentation Index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI, physical characteristics, and abstinence period. The current study was carried out among male patients visiting an infertility clinic at SDM College of Medical Sciences and Hospital, Dharwad.The present has shownno statistically significant association between DFI and socio-demographic characteristics like age, married life, contraceptive usage, sexual factors, personal habits, chronic illness, BMI, and physical characteristics of semen analysis like liquefaction and viscosity of the study participants. DFI categories and semen traits including normal forms, head defects, tail defects, amorphous forms, droplet forms, and viable sperms had different means, however these differences (p=0.4378) were not statistically significant.
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精子 DNA 碎片指数 (DFI) 与人口统计学特征、性史、社会习惯、慢性疾病和体重指数之间的相关性:横断面研究
:在对精液所有标准参数都正常的不育男性进行评估时,发现相当一部分不育男性的 DNA 损伤程度增加,可能会对生育能力产生不利影响。目的:评估精子 DNA 碎片指数(DFI)与人口统计学特征、性史、社会习惯、慢性疾病、体重指数、身体特征和禁欲时间之间的相关性。本研究在达尔瓦德 SDM 医学院和医院不孕不育门诊就诊的男性患者中进行。研究结果表明,精子 DNA 碎片指数(DFI)与研究对象的年龄、婚姻生活、避孕药具使用情况、性因素、个人习惯、慢性疾病、体重指数等社会人口学特征以及精液分析的液化度和粘度等物理特征之间没有统计学意义上的显著关联。DFI 类别和精液特征(包括正常形态、头部缺陷、尾部缺陷、无定形形态、液滴形态和有活力精子)的平均值不同,但这些差异(P=0.4378)在统计学上并不显著。
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