How complicated can be a case with immune thrombocytopenic purpura?: postsplenectomy arterial thrombosis.

IF 1.2 4区 医学 Q4 HEMATOLOGY Blood Coagulation & Fibrinolysis Pub Date : 2024-06-01 Epub Date: 2024-02-21 DOI:10.1097/MBC.0000000000001290
Ahmet Deniz Kaya, Oguzhan Tekin, Yasin Colak, Istemi Serin
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Abstract

Arterial thrombus associated with the surgery can be seen in postsplenectomy cases, but there is no clear data in patients diagnosed with immune thrombocytopenic purpura (ITP). A 52-year-old female patient was admitted to the emergency department due to ecchymotic skin changes. Her initial platelet count was 6000/mm 3 ; after two courses of high dose-dexamethasone, intravenous immunoglobulin and rituximab, splenectomy was planned for the patient whose platelet count was again <40 000/mm 3 . She presented to the emergency department with complaints of pain and pallor in the right arm in the second week of follow-up. There was a mural thrombus that caused approximately 50% stenosis in the lumen at the division site in the aortic arch, proximal of the right subclavian artery. The patient's clinic was found to be associated with the presence of an aberrant right subclavian artery and postoperative thrombocytosis/inflammation after elimination other prothrombotic conditions.

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免疫性血小板减少性紫癜病例有多复杂?
在脾切除术后病例中可以看到与手术相关的动脉血栓,但在确诊为免疫性血小板减少性紫癜(ITP)的患者中却没有明确的数据。一名 52 岁的女性患者因皮肤瘀斑而被送入急诊科。她最初的血小板计数为 6000/mm3;经过两个疗程的大剂量地塞米松、静脉注射免疫球蛋白和利妥昔单抗治疗后,计划对患者进行脾切除术,但患者的血小板计数再次升高。
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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
111
审稿时长
4-8 weeks
期刊介绍: Blood Coagulation & Fibrinolysis is an international fully refereed journal that features review and original research articles on all clinical, laboratory and experimental aspects of haemostasis and thrombosis. The journal is devoted to publishing significant developments worldwide in the field of blood coagulation, fibrinolysis, thrombosis, platelets and the kininogen-kinin system, as well as dealing with those aspects of blood rheology relevant to haemostasis and the effects of drugs on haemostatic components
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