The updated role of budesonide in managing children and adolescents with allergic rhinitis.

IF 1 Q3 PEDIATRICS Minerva Pediatrics Pub Date : 2024-08-01 Epub Date: 2024-02-26 DOI:10.23736/S2724-5276.24.07538-4
Giorgio Ciprandi
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Abstract

Allergic rhinitis (AR) is a prevalent disease in childhood and adolescence. A type 2 inflammation characterizes AR and, mainly, sustains nasal obstruction. Budesonide aqueous nasal spray (BANS) is an intranasal corticosteroid (INCS) available since the early 1980s. BANS is indicated for treating allergic rhinitis. There is evidence about its efficacy in treating children and adolescents with seasonal and perennial AR. In addition, BANS is safe with negligible local and systemic side effects. Recent guidelines for patients with AR recommend the use of INCS as first line in many situations. In particular, AR patients (and their parents) may assess the perception of symptoms' severity using the Visual Analog Scale (VAS). A score ≥5/10 means uncontrolled symptoms and requires adequate treatment. BANS could appropriately be used in patients with uncontrolled symptoms and/or moderate/severe nasal obstruction. In conclusion, BANS represents a valuable option in managing children and adolescents with AR.

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布地奈德在治疗儿童和青少年过敏性鼻炎中的最新作用。
过敏性鼻炎(AR)是儿童和青少年时期的一种常见病。2 型炎症是过敏性鼻炎的特征,主要导致鼻腔阻塞。布地奈德水鼻喷雾剂(BANS)是一种鼻内皮质类固醇(INCS),早在 20 世纪 80 年代初就已上市。BANS 适用于治疗过敏性鼻炎。有证据表明,它对治疗患有季节性和常年性过敏性鼻炎的儿童和青少年有效。此外,BANS 也很安全,对局部和全身的副作用微乎其微。最近针对 AR 患者的指南建议在许多情况下将 INCS 作为一线药物使用。特别是,AR 患者(及其家长)可使用视觉模拟量表(VAS)评估症状的严重程度。得分≥5/10 表示症状未得到控制,需要进行适当治疗。BANS 可适当用于症状无法控制和/或中度/重度鼻塞的患者。总之,BANS 是治疗儿童和青少年 AR 患者的重要选择。
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