P- 43 HCV TESTING AND TREATMENT IN FOUR BRAZILIANS’ CORRECTIONAL SETTINGS

IF 3.7 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Annals of hepatology Pub Date : 2024-02-01 DOI:10.1016/j.aohep.2023.101230
Joao Batista da Silva , Eric Soares , Alexandre Munhoz , Raquel Dalpaz Dias , Ana Paula Moraes da Silva Barrufi , Janieri Rosso Dassoler , Tiane Ramos do Canto , Thaís Alves Martins Candido , Maria da Penha da Rosa , Cleber Monteiro Ávila , Eder Gonçalves Portes , Fabiana de Brida , Patricia Rodrigues Oenning
{"title":"P- 43 HCV TESTING AND TREATMENT IN FOUR BRAZILIANS’ CORRECTIONAL SETTINGS","authors":"Joao Batista da Silva ,&nbsp;Eric Soares ,&nbsp;Alexandre Munhoz ,&nbsp;Raquel Dalpaz Dias ,&nbsp;Ana Paula Moraes da Silva Barrufi ,&nbsp;Janieri Rosso Dassoler ,&nbsp;Tiane Ramos do Canto ,&nbsp;Thaís Alves Martins Candido ,&nbsp;Maria da Penha da Rosa ,&nbsp;Cleber Monteiro Ávila ,&nbsp;Eder Gonçalves Portes ,&nbsp;Fabiana de Brida ,&nbsp;Patricia Rodrigues Oenning","doi":"10.1016/j.aohep.2023.101230","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and Objectives</h3><p>The unfavorable hygiene conditions and inadequate health monitoring in many prisons increase the risk of infections such as HIV, syphilis, tuberculosis, and hepatitis B or C. The prevalence of hepatitis C in prisoners worldwide was estimated to be 17.7% (1). Variable access to correctional healthcare resources, limited funding, high inmate turnover rates, and deficient follow- up care after release are a few factors that confound HCV control and prevention in this group. In Brazil, The Criminal Execution Law 7210 of July 11, 1984, in Article 14, grants inmates preventive and curative medical, dental, and pharmacological healthcare. This study aimed to investigate the prevalence of hepatitis C antibodies (HCV-ab) among the 4-prison population in Brazil's South region.</p></div><div><h3>Materials and Methods</h3><p>Participants were interviewed and opt-out provided blood samples and underwent rapid HCV testing and confirmatory testing when indicated. Persons with chronic infection were referred to treatment inside the correctional facility.</p></div><div><h3>Results</h3><p>In 2022, from October to December, 2,057 inmates were tested in 4 correctional facilities in Santa Catarina and Rio Grande do Sul State, with an overall prevalence of 2,52% (52/2,057), 3 times higher than in the general population in Brazil. In the prison with a higher number of tests (762) 95% of the inmates are female, the mean age of 34 y/o, and the HCV-ab prevalence (2,49%) was similar to males’ prisons (2,54%).</p></div><div><h3>Conclusions</h3><p>It is necessary to control HCV in prisons by screening and treating prisoners to reach WHO 2030 elimination goals. Diagnosis of chronic HCV in correctional settings followed by linkage to care and successful antiviral treatment can ultimately reduce the risk of liver-related and extrahepatic complications and potentially decrease HCV transmission in correctional facilities and the community after release.</p></div>","PeriodicalId":7979,"journal":{"name":"Annals of hepatology","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1665268123003332/pdfft?md5=4a8cd0d3b841c0f2fc2ca4f5fea28cef&pid=1-s2.0-S1665268123003332-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of hepatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1665268123003332","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction and Objectives

The unfavorable hygiene conditions and inadequate health monitoring in many prisons increase the risk of infections such as HIV, syphilis, tuberculosis, and hepatitis B or C. The prevalence of hepatitis C in prisoners worldwide was estimated to be 17.7% (1). Variable access to correctional healthcare resources, limited funding, high inmate turnover rates, and deficient follow- up care after release are a few factors that confound HCV control and prevention in this group. In Brazil, The Criminal Execution Law 7210 of July 11, 1984, in Article 14, grants inmates preventive and curative medical, dental, and pharmacological healthcare. This study aimed to investigate the prevalence of hepatitis C antibodies (HCV-ab) among the 4-prison population in Brazil's South region.

Materials and Methods

Participants were interviewed and opt-out provided blood samples and underwent rapid HCV testing and confirmatory testing when indicated. Persons with chronic infection were referred to treatment inside the correctional facility.

Results

In 2022, from October to December, 2,057 inmates were tested in 4 correctional facilities in Santa Catarina and Rio Grande do Sul State, with an overall prevalence of 2,52% (52/2,057), 3 times higher than in the general population in Brazil. In the prison with a higher number of tests (762) 95% of the inmates are female, the mean age of 34 y/o, and the HCV-ab prevalence (2,49%) was similar to males’ prisons (2,54%).

Conclusions

It is necessary to control HCV in prisons by screening and treating prisoners to reach WHO 2030 elimination goals. Diagnosis of chronic HCV in correctional settings followed by linkage to care and successful antiviral treatment can ultimately reduce the risk of liver-related and extrahepatic complications and potentially decrease HCV transmission in correctional facilities and the community after release.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
P-43 巴西四个惩教机构的艾滋病毒检测和治疗情况
导言和目标许多监狱卫生条件差、健康监测不足,增加了感染艾滋病、梅毒、肺结核、乙型或丙型肝炎等疾病的风险。获得惩教医疗资源的机会不一、资金有限、囚犯更替率高以及释放后的后续护理不足等因素都是影响该群体丙型肝炎病毒控制和预防的因素。在巴西,1984 年 7 月 11 日颁布的第 7210 号《刑事执行法》第 14 条规定为囚犯提供预防和治疗性医疗、牙科和药物保健。本研究旨在调查巴西南部地区四所监狱人群中丙型肝炎抗体(HCV-ab)的流行情况。材料与方法对参与者进行访谈,并选择不提供血液样本,接受快速 HCV 检测和有指征时的确证检测。结果2022年10月至12月,圣卡塔琳娜州和南里奥格兰德州的4所监狱共检测了2057名囚犯,总患病率为2.52%(52/2057),是巴西普通人群的3倍。在检测人数较多的监狱(762 人)中,95% 的囚犯为女性,平均年龄为 34 岁/o,HCV-ab 感染率(2.49%)与男性监狱(2.54%)相似。在惩教环境中诊断出慢性丙型肝炎病毒,然后进行联系护理和成功的抗病毒治疗,最终可以降低肝脏相关并发症和肝外并发症的风险,并有可能减少丙型肝炎病毒在惩教机构和出狱后在社区的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Annals of hepatology
Annals of hepatology 医学-胃肠肝病学
CiteScore
7.90
自引率
2.60%
发文量
183
审稿时长
4-8 weeks
期刊介绍: Annals of Hepatology publishes original research on the biology and diseases of the liver in both humans and experimental models. Contributions may be submitted as regular articles. The journal also publishes concise reviews of both basic and clinical topics.
期刊最新文献
Editorial board Alcohol-related liver disease: A global perspective Hepatitis B virus X protein differentially regulates the angiogenesis of Hepatocellular Carcinoma through p53-VEGF axis according to glucose levels Helicobacter pylori cagA/vacAs1-m1 strain is associated with high risk of fibrosis in metabolic-dysfunction-associated steatotic liver disease Relationship between sarcopenia and metabolic dysfunction-associated steatotic liver disease (MASLD): A systematic review and meta-analysis
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1