FIT for the future

IF 2.4 Q3 GASTROENTEROLOGY & HEPATOLOGY Frontline Gastroenterology Pub Date : 2024-02-26 DOI:10.1136/flgastro-2023-102586
Robert Logan, Charles Andrews
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Abstract

Based on evidence from patients with both high-risk and low-risk symptoms of colorectal cancer (CRC), National Institute of Clinical Excellence (NICE) NG56 (quantitative faecal immunochemical testing (FIT) to guide CRC referral in primary care) places FIT at the heart of CRC diagnosis in primary care.1 When fully implemented, it should improve the diagnosis of CRC by identifying those at increased risk and reduce the demand for unnecessary (low value) endoscopy in those at low risk. However, greater use of FIT as a triage tool in primary care will lead to two challenges: first, how to manage any increased demand arising from widespread use of FIT in patients outside of NG56 recommendations, and second, how to manage patients with symptoms but who are ‘FIT negative’ (and not anaemic) and who represent the vast majority of patients referred for suspected cancer. In their publication, Bashir et al provide reassuring real-world evidence from the north-east of England which validates the use of FIT and propose cancer detection rate (CDR) as a new …
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面向未来的 FIT
国家临床优化研究所 (NICE) 的 NG56(定量粪便免疫化学检验 (FIT),用于指导初级医疗机构的 CRC 转诊)基于高风险和低风险结直肠癌 (CRC) 症状患者的证据,将 FIT 作为初级医疗机构 CRC 诊断的核心1 。然而,在初级医疗中更多地使用 FIT 作为分诊工具将带来两个挑战:第一,如何管理因在 NG56 建议范围之外的患者中广泛使用 FIT 而增加的需求;第二,如何管理有症状但 FIT 为 "阴性"(且不贫血)的患者,这些患者占疑似癌症转诊患者的绝大多数。在他们的出版物中,Bashir 等人提供了来自英格兰东北部的令人欣慰的实际证据,证实了 FIT 的使用,并提出将癌症检出率 (CDR) 作为一种新的 ...
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来源期刊
Frontline Gastroenterology
Frontline Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.70
自引率
11.50%
发文量
93
期刊介绍: Frontline Gastroenterology publishes articles that accelerate adoption of innovative and best practice in the fields of gastroenterology and hepatology. Frontline Gastroenterology is especially interested in articles on multidisciplinary research and care, focusing on both retrospective assessments of novel models of care as well as putative future directions of best practice. Specifically Frontline Gastroenterology publishes articles in the domains of clinical quality, patient experience, service provision and medical education.
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