Propolis and its therapeutic effects on renal diseases: A review.

IF 2.1 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Iranian Journal of Basic Medical Sciences Pub Date : 2024-01-01 DOI:10.22038/IJBMS.2024.73081.15880

Fatemeh Salami, Reza Mohebbati, Sara Hosseinian, Samira Shahraki, Hossein Hossienzadeh, Abolfazl Khajavi Rad

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Abstract

Propolis is produced by bees using a mixture of bees wax and saliva. It contains several bioactive compounds that mainly induce anti-oxidant and anti-inflammatory effects. In this review, we aimed to investigate the effects of propolis on kidney diseases. We used "Kidney", "Disease", "Propolis", "Renal", "Constituent", "Mechanism", "Infection", and other related keywords as the main keywords to search for works published before July 2023 in Google scholar, Scopus, and Pubmed databases. The search terms were selected according to Medical Subject Headings (MeSH). This review showed that propolis affects renal disorders with inflammatory and oxidative etiology due to its bioactive compounds, mainly flavonoids and polyphenols. There have been few studies on the effects of propolis on kidney diseases; nevertheless, the available studies are integrated in this review. Overall, propolis appears to be effective against several renal diseases through influencing mechanisms such as apoptosis, oxidative balance, and inflammation.

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蜂胶及其对肾病的治疗作用：综述。

蜂胶是蜜蜂利用蜂蜡和唾液的混合物生产出来的。它含有多种生物活性化合物，主要具有抗氧化和消炎作用。在这篇综述中，我们旨在研究蜂胶对肾脏疾病的影响。我们以 "肾脏"、"疾病"、"蜂胶"、"肾脏"、"成分"、"机制"、"感染 "和其他相关关键词为主要关键词，在 Google scholar、Scopus 和 Pubmed 数据库中检索 2023 年 7 月之前发表的作品。检索词根据医学主题词表（MeSH）进行选择。综述显示，蜂胶的生物活性化合物（主要是类黄酮和多酚）可影响炎症和氧化病因引起的肾脏疾病。有关蜂胶对肾脏疾病影响的研究很少；不过，本综述对现有研究进行了整合。总体而言，蜂胶似乎可通过影响细胞凋亡、氧化平衡和炎症等机制，有效防治多种肾脏疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Basic Medical Sciences MEDICINE, RESEARCH & EXPERIMENTAL-PHARMACOLOGY & PHARMACY

CiteScore

4.00

自引率

4.50%

发文量

142

审稿时长

6-12 weeks

期刊介绍： The Iranian Journal of Basic Medical Sciences (IJBMS) is a peer-reviewed, monthly publication by Mashhad University of Medical Sciences (MUMS), Mashhad, Iran . The Journal of "IJBMS” is a modern forum for scientific communication. Data and information, useful to investigators in any discipline in basic medical sciences mainly including Anatomical Sciences, Biochemistry, Genetics, Immunology, Microbiology, Pathology, Pharmacology, Pharmaceutical Sciences, and Physiology, will be published after they have been peer reviewed. This will also include reviews and multidisciplinary research.