Onychopapilloma: a single medical center experience in Southern Taiwan.

Po-Ta Lai, Yung-Wei Chang, Shang-Hung Lin
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Abstract

Background: Onychopapilloma is an uncommon benign tumor of the nail bed and the distal matrix. Objectives: We aimed to investigate the clinical and pathological features of onychopapilloma in Taiwan.Materials and methods: We conducted a retrospective analysis of 12 patients with histopathologically proven onychopapilloma in a medical center in southern Taiwan from 2017 to 2023. Results: This case series consisted of 5 men and 7 women aged 29 to 38, with a mean age of 41.25 years. The clinical features were as follows: distal subungual hyperkeratosis (100%), longitudinal erythronychia (50%), longitudinal leukonychia (50 %), distal onycholysis (41%), and distal nail plate fissuring (41%). The duration of the disease varied greatly, ranging from 1 month to several years. Most patients were asymptomatic (58%), while some presented tenderness (41%). Fingernail involvement was more prevalent than toe involvement, with the thumb being the most commonly affected site. Most of the patients presented with a solitary onychopapilloma. None of the seven patients who underwent surgery and were available for follow-up experienced recurrence.Conclusions: This study highlights that longitudinal erythronychia and leukonychia emerged as the predominant clinical presentations of onychopapilloma. Furthermore, our findings suggest that surgical excision appears to be an effective method for onychopapilloma.

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颧骨乳头状瘤:台湾南部一家医疗中心的经验。
背景:甲沟乳头状瘤是甲床和远端基质中一种不常见的良性肿瘤。目的:我们旨在调查台湾甲沟乳头状瘤的临床和病理特征:我们旨在调查台湾甲沟乳头状瘤的临床和病理特征:我们对2017年至2023年台湾南部一家医疗中心的12例经组织病理学证实的甲沟乳头状瘤患者进行了回顾性分析。结果:该病例系列包括 5 名男性和 7 名女性,年龄在 29 岁至 38 岁之间,平均年龄为 41.25 岁。临床特征如下:远端甲下角化过度(100%)、纵向红斑(50%)、纵向白斑(50%)、远端甲癣(41%)和远端甲板裂开(41%)。病程长短不一,从一个月到数年不等。大多数患者无症状(58%),但有些患者有压痛(41%)。手指甲受累比脚趾受累更普遍,拇指是最常受累的部位。大多数患者表现为单发的趾甲骨乳头状瘤。在接受手术并接受随访的七名患者中,没有一人复发:本研究强调,纵向红斑和白斑是痣状软骨瘤的主要临床表现。此外,我们的研究结果表明,手术切除似乎是治疗霰粒肿的有效方法。
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