The challenges for early intervention and its effects on the prognosis of autism spectrum disorder: a systematic review.

Q3 Medicine Dementia e Neuropsychologia Pub Date : 2024-02-09 eCollection Date: 2024-01-01 DOI:10.1590/1980-5764-DN-2023-0034
Jackson Frederico Pires, Caroline Cajuela Grattão, Regiane Maria Ribeiro Gomes
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Abstract

Autism spectrum disorder (ASD) is expressed with neurobehavioral symptoms of different degrees of intensity. It is estimated that, for every three cases detected, there are two cases that reach adulthood without treatment.

Objective: To establish what challenges are still present in the implementation of early intervention (EI) and its effects on the prognosis of ASD.

Methods: A systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (Prisma) methodology was carried out in the PubMed and ScienceDirect databases in January 2023. The search keywords were "autism spectrum disorder", "early intervention" and "prognosis".

Results: Sixteen studies were included, two randomized and 14 non-randomized. Knowledge about the signs of ASD, diagnostic and therapeutic methods, age at the start of treatment, and socioeconomic factors were the main challenges encountered in the implementation of the EI.

Conclusion: EI is capable of modifying the prognosis of ASD and challenges in its implementation persist, especially in developing regions with low socioeconomic status.

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早期干预的挑战及其对自闭症谱系障碍预后的影响:系统综述。
自闭症谱系障碍(ASD)表现为不同程度的神经行为症状。据估计,每发现三例自闭症患者,就有两例在没有治疗的情况下长大成人:目的:确定早期干预(EI)的实施仍面临哪些挑战及其对 ASD 预后的影响:方法:2023 年 1 月在 PubMed 和 ScienceDirect 数据库中采用系统综述和元分析首选报告项目(Prisma)方法进行了系统综述。搜索关键词为 "自闭症谱系障碍"、"早期干预 "和 "预后":结果:共纳入 16 项研究,其中 2 项为随机研究,14 项为非随机研究。对自闭症迹象的了解、诊断和治疗方法、开始治疗时的年龄以及社会经济因素是实施早期干预所遇到的主要挑战:EI能够改变ASD的预后,但在实施过程中仍面临挑战,尤其是在社会经济地位较低的发展中地区。
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来源期刊
Dementia e Neuropsychologia
Dementia e Neuropsychologia Medicine-Geriatrics and Gerontology
CiteScore
2.20
自引率
0.00%
发文量
58
审稿时长
8 weeks
期刊介绍: Dementia top Neuropsychologia the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and of the Brazilian Association of Geriatric Neuropsychiatry, is published by the "Associação Neurologia Cognitiva e do Comportamento", a nonprofit Brazilian association. Regularly published on March, June, September, and December since 2007.
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