Life-History Trade-Offs in Drosophila: Flies Select a Diet to Maximize Reproduction at the Expense of Lifespan.

Olha Strilbytska, Ihor Yurkevych, Uliana Semaniuk, Dmytro Gospodaryov, Stephen J Simpson, Oleh Lushchak
{"title":"Life-History Trade-Offs in Drosophila: Flies Select a Diet to Maximize Reproduction at the Expense of Lifespan.","authors":"Olha Strilbytska, Ihor Yurkevych, Uliana Semaniuk, Dmytro Gospodaryov, Stephen J Simpson, Oleh Lushchak","doi":"10.1093/gerona/glae057","DOIUrl":null,"url":null,"abstract":"<p><p>Macronutrient intake impacts physiology, behavior, and gene expression in a wide range of organisms. We used the response surface methodology to compare how life history traits, lifespan, and reproduction differ as a function of protein and carbohydrate intakes under choice and no-choice feeding regimens in the fruit fly, Drosophila melanogaster. We found that when offered a choice of nutritionally complementary foods mated female flies regulated toward a protein to carbohydrate ratio (P:C) that was associated with shortened lifespan and maximal egg production when compared to response surfaces derived from flies fed 1 of a range of fixed diets differing in P:C (no-choice regimen). This difference in lifespan between choice and no-choice feeding was not seen in males or virgin flies, reflecting the fact that increased protein intake is triggered by mating to support egg production. However, whereas in mated females a higher P:C intake was associated with greater egg production under both choice and no-choice feeding, contrary to expectations, choice-fed mated flies laid fewer eggs than no-choice flies on equivalent macronutrient intakes, perhaps reflecting that they had to ingest twice the volume of food to attain an equivalent intake of nutrients than no-choice flies on a diet of equivalent P:C ratio.</p>","PeriodicalId":94243,"journal":{"name":"The journals of gerontology. Series A, Biological sciences and medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11491752/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The journals of gerontology. Series A, Biological sciences and medical sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/gerona/glae057","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Macronutrient intake impacts physiology, behavior, and gene expression in a wide range of organisms. We used the response surface methodology to compare how life history traits, lifespan, and reproduction differ as a function of protein and carbohydrate intakes under choice and no-choice feeding regimens in the fruit fly, Drosophila melanogaster. We found that when offered a choice of nutritionally complementary foods mated female flies regulated toward a protein to carbohydrate ratio (P:C) that was associated with shortened lifespan and maximal egg production when compared to response surfaces derived from flies fed 1 of a range of fixed diets differing in P:C (no-choice regimen). This difference in lifespan between choice and no-choice feeding was not seen in males or virgin flies, reflecting the fact that increased protein intake is triggered by mating to support egg production. However, whereas in mated females a higher P:C intake was associated with greater egg production under both choice and no-choice feeding, contrary to expectations, choice-fed mated flies laid fewer eggs than no-choice flies on equivalent macronutrient intakes, perhaps reflecting that they had to ingest twice the volume of food to attain an equivalent intake of nutrients than no-choice flies on a diet of equivalent P:C ratio.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
果蝇的生活史权衡:果蝇选择饮食以最大限度地繁殖为代价。
宏量营养素摄入会影响多种生物的生理、行为、生理学和基因表达。我们利用响应面方法比较了果蝇在有选择和无选择喂养方案下,蛋白质和碳水化合物摄入量对其生活史特征、寿命和繁殖的影响。我们发现,当交配雌蝇可选择营养互补的食物时,其蛋白质与碳水化合物的比例(P:C)与喂食一系列P:C不同的固定食物(无选择喂食方案)的雌蝇的反应面相比,蛋白质与碳水化合物的比例(P:C)与寿命缩短和最大产卵量有关。雄蝇和处女蝇的寿命在有选择喂养和无选择喂养之间没有差异,这反映了交配会增加蛋白质摄入量以支持产卵。然而,在交配雌蝇中,较高的 P:C 摄入量与选择和非选择喂养条件下更高的产卵量有关,但与预期相反,选择喂养的交配蝇比非选择喂养的蝇在同等宏量营养素摄入量下产卵量要少,这可能反映了它们必须摄入两倍的食物量才能达到同等的营养素摄入量,而非选择喂养的蝇在同等 P:C 比率的饮食条件下产卵量要比非选择喂养的蝇少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Trend in Respite Use by Race Among Caregivers for People Living With Dementia. Projecting Long-Term Care Costs Among Older Adults With ADL Disabilities and Cognitive Impairment in China. Care Need, Caregiver Availability, and Care Receipt: Variations Across Countries and Over Time in Three Middle-Income Countries. Trends in Memory Function and Memory Impairment Among Older Adults in the United States and Europe, 1996-2018. Addressing Practice Effects in Population-Based Studies of Trends in Late-Life Dementia and Cognitive Impairment.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1