A Bayesian approach to uncover spatio-temporal determinants of heterogeneity in repeated cross-sectional health surveys

Mattia Stival, Lorenzo Schiavon, Stefano Campostrini
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Abstract

In several countries, including Italy, a prominent approach to population health surveillance involves conducting repeated cross-sectional surveys at short intervals of time. These surveys gather information on the health status of individual respondents, including details on their behaviors, risk factors, and relevant socio-demographic information. While the collected data undoubtedly provides valuable information, modeling such data presents several challenges. For instance, in health risk models, it is essential to consider behavioral information, spatio-temporal dynamics, and disease co-occurrence. In response to these challenges, our work proposes a multivariate spatio-temporal logistic model for chronic disease diagnoses. Predictors are modeled using individual risk factor covariates and a latent individual propensity to the disease. Leveraging a state space formulation of the model, we construct a framework in which spatio-temporal heterogeneity in regression parameters is informed by exogenous spatial information, corresponding to different spatial contextual risk factors that may affect health and the occurrence of chronic diseases in different ways. To explore the utility and the effectiveness of our method, we analyze behavioral and risk factor surveillance data collected in Italy (PASSI), which is well-known as a country characterized by high peculiar administrative, social and territorial diversities reflected on high variability in morbidity among population subgroups.
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贝叶斯方法揭示重复横截面健康调查中异质性的时空决定因素
在包括意大利在内的一些国家,人口健康监测的一个重要方法是在短时间内重复进行横断面调查。这些调查收集受访者个人健康状况的信息,包括行为细节、风险因素和相关社会人口信息。虽然收集到的数据无疑提供了有价值的信息,但对这些数据进行建模却面临着一些挑战。例如,在健康风险模型中,必须考虑行为信息、时空动态和疾病共存性。为了应对这些挑战,我们的研究提出了一种用于慢性疾病诊断的多变量时空逻辑模型。预测因子使用个人风险因素协变量和潜在的个人疾病倾向进行建模。利用该模型的状态空间表述,我们构建了一个框架,在该框架中,回归参数的时空异质性由外生空间信息提供,这些外生空间信息与可能以不同方式影响健康和慢性病发生的不同空间环境风险因素相对应。为了探索我们的方法的实用性和有效性,我们分析了在意大利收集的行为和风险因素监测数据(PASSI),众所周知,意大利是一个具有高度特殊行政、社会和地域多样性的国家,这反映在人口亚群之间发病率的高度不稳定性上。
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